Platinum in PDB 7djw: uc(Nmr) Solution Structure of the 1:1 Complex of A Platinum(II) Compound Bound to 3'-End of MYC1234 G-Quadruplex Reveals the Mechanism of Conformational Switch and Dynamic Binding of G-Quadruplex

The binding sites of Platinum atom in the uc(Nmr) Solution Structure of the 1:1 Complex of A Platinum(II) Compound Bound to 3'-End of MYC1234 G-Quadruplex Reveals the Mechanism of Conformational Switch and Dynamic Binding of G-Quadruplex (pdb code 7djw). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the uc(Nmr) Solution Structure of the 1:1 Complex of A Platinum(II) Compound Bound to 3'-End of MYC1234 G-Quadruplex Reveals the Mechanism of Conformational Switch and Dynamic Binding of G-Quadruplex, PDB code: 7djw:

Platinum binding site 1 out of 1 in the uc(Nmr) Solution Structure of the 1:1 Complex of A Platinum(II) Compound Bound to 3'-End of MYC1234 G-Quadruplex Reveals the Mechanism of Conformational Switch and Dynamic Binding of G-Quadruplex


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of uc(Nmr) Solution Structure of the 1:1 Complex of A Platinum(II) Compound Bound to 3'-End of MYC1234 G-Quadruplex Reveals the Mechanism of Conformational Switch and Dynamic Binding of G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt101 b:0.4 occ:1.00 PT A:H9C101 0.0 0.4 1.0 N4 A:H9C101 2.2 0.4 1.0 N1 A:H9C101 2.2 0.4 1.0 N3 A:H9C101 2.2 0.4 1.0 N2 A:H9C101 2.2 0.4 1.0 C12 A:H9C101 3.0 0.5 1.0 C23 A:H9C101 3.0 0.4 1.0 C11 A:H9C101 3.0 0.5 1.0 C24 A:H9C101 3.0 0.4 1.0 C22 A:H9C101 3.3 0.4 1.0 C13 A:H9C101 3.3 0.4 1.0 C10 A:H9C101 3.3 0.4 1.0 C1 A:H9C101 3.3 0.5 1.0 H22 A:H9C101 3.4 0.4 1.0 H13 A:H9C101 3.4 0.4 1.0 H10 A:H9C101 3.4 0.4 1.0 H1 A:H9C101 3.4 0.5 1.0 O6 A:DG5 3.7 0.5 1.0 O6 A:DG18 4.1 0.5 1.0 C7 A:H9C101 4.4 0.5 1.0 O6 A:DG12 4.4 0.5 1.0 C19 A:H9C101 4.4 0.4 1.0 C4 A:H9C101 4.4 0.5 1.0 C16 A:H9C101 4.4 0.5 1.0 C6 A:DG5 4.4 0.5 1.0 H1 A:DG18 4.5 0.5 1.0 C9 A:H9C101 4.6 0.5 1.0 C21 A:H9C101 4.6 0.4 1.0 C14 A:H9C101 4.6 0.5 1.0 C2 A:H9C101 4.6 0.5 1.0 C6 A:DG18 4.6 0.5 1.0 H3 A:DT10 4.6 0.7 1.0 H1 A:DG5 4.6 0.5 1.0 O6 A:DG9 4.7 0.5 1.0 H72 A:DT19 4.7 0.9 1.0 N1 A:DG18 4.8 0.5 1.0 H73 A:DT19 4.8 1.0 1.0 H1 A:DG12 4.9 0.5 1.0 N1 A:DG5 4.9 0.5 1.0

W.Liu, B.C.Zhu, L.Y.Liu, X.Y.Xia, Z.W.Mao. G-Quadruplex Structural Transition Driven By A Platinum Compound. Nucleic Acids Res. V. 50 7816 2022.
ISSN: ESSN 1362-4962
PubMed: 35766415
DOI: 10.1093/NAR/GKAC572