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Platinum in PDB 1a84: uc(Nmr) Solution Structure of A Dna Dodecamer Duplex Containing A Cis- Diammineplatinum(II) D(Gpg) Intrastrand Cross-Link, the Major Adduct of the Anticancer Drug Cisplatin, 1 Structure

Platinum Binding Sites:

The binding sites of Platinum atom in the uc(Nmr) Solution Structure of A Dna Dodecamer Duplex Containing A Cis- Diammineplatinum(II) D(Gpg) Intrastrand Cross-Link, the Major Adduct of the Anticancer Drug Cisplatin, 1 Structure (pdb code 1a84). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the uc(Nmr) Solution Structure of A Dna Dodecamer Duplex Containing A Cis- Diammineplatinum(II) D(Gpg) Intrastrand Cross-Link, the Major Adduct of the Anticancer Drug Cisplatin, 1 Structure, PDB code: 1a84:

Platinum binding site 1 out of 1 in 1a84

Go back to Platinum Binding Sites List in 1a84
Platinum binding site 1 out of 1 in the uc(Nmr) Solution Structure of A Dna Dodecamer Duplex Containing A Cis- Diammineplatinum(II) D(Gpg) Intrastrand Cross-Link, the Major Adduct of the Anticancer Drug Cisplatin, 1 Structure


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of uc(Nmr) Solution Structure of A Dna Dodecamer Duplex Containing A Cis- Diammineplatinum(II) D(Gpg) Intrastrand Cross-Link, the Major Adduct of the Anticancer Drug Cisplatin, 1 Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt13

b:0.0
occ:1.00
PT1 A:CPT13 0.0 0.0 1.0
N7 A:DG6 2.0 0.0 1.0
N1 A:CPT13 2.0 0.0 1.0
N2 A:CPT13 2.0 0.0 1.0
N7 A:DG7 2.1 0.0 1.0
H12 A:CPT13 2.6 0.0 1.0
H22 A:CPT13 2.6 0.0 1.0
H21 A:CPT13 2.6 0.0 1.0
H11 A:CPT13 2.6 0.0 1.0
H13 A:CPT13 2.6 0.0 1.0
H23 A:CPT13 2.6 0.0 1.0
C8 A:DG6 3.0 0.0 1.0
C8 A:DG7 3.0 0.0 1.0
C5 A:DG7 3.1 0.0 1.0
C5 A:DG6 3.1 0.0 1.0
H8 A:DG6 3.1 0.0 1.0
H8 A:DG7 3.2 0.0 1.0
O6 A:DG7 3.5 0.0 1.0
O6 A:DG6 3.5 0.0 1.0
C6 A:DG7 3.6 0.0 1.0
C6 A:DG6 3.6 0.0 1.0
N9 A:DG7 4.1 0.0 1.0
N9 A:DG6 4.2 0.0 1.0
C4 A:DG7 4.2 0.0 1.0
C4 A:DG6 4.2 0.0 1.0
H71 A:DT5 4.7 0.0 1.0
H41 B:DC18 4.9 0.0 1.0
N1 A:DG7 5.0 0.0 1.0
N1 A:DG6 5.0 0.0 1.0

Reference:

A.Gelasco, S.J.Lippard. uc(Nmr) Solution Structure of A Dna Dodecamer Duplex Containing A Cis-Diammineplatinum(II) D(Gpg) Intrastrand Cross-Link, the Major Adduct of the Anticancer Drug Cisplatin. Biochemistry V. 37 9230 1998.
ISSN: ISSN 0006-2960
PubMed: 9649303
DOI: 10.1021/BI973176V
Page generated: Wed Dec 16 02:03:34 2020

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