Platinum in the structure of Solution Structure of Intrastrand Cisplatin-Crosslinked Dna Octamer D(Cctg*G*Tcc):D(Ggaccagg), uc(Nmr), Minimized Average Structure (pdb 1au5)

The binding sites of Platinum atom in the structure of Solution Structure of Intrastrand Cisplatin-Crosslinked Dna Octamer D(Cctg*G*Tcc):D(Ggaccagg), uc(Nmr), Minimized Average Structure (pdb code 1au5). This binding sites where shown with 5.0 Angstroms radius around Platinum atom. The 1au5 structure was solved by D.YANG, S.S.G.E.VAN BOOM, J.REEDIJK, J.H.VAN BOOM, A.H.-J.WANG, with NMR in Solution technique. Platinum Binding Sites: Platinum binding site 1 out of 1 in 1au5 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Platinum in the PDB 1au5. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Dt3, A: Dg4, A: Dg5, A: Dt6, B: Dc12, A: Cpt17, conact list: Atom Atom Distance (A) Pt H2' A:Dt3 4.35 Pt N9 A:Dg4 4.12 Pt C8 A:Dg4 2.92 Pt C6 A:Dg4 3.57 Pt C5 A:Dg4 3.04 Pt H3' A:Dg4 4.97 Pt C4 A:Dg4 4.17 Pt H8 A:Dg4 3.03 Pt N1 A:Dg4 4.90 Pt N7 A:Dg4 1.98 Pt O6 A:Dg4 3.41 Pt N9 A:Dg5 4.14 Pt C8 A:Dg5 2.95 Pt C6 A:Dg5 3.48 Pt C5 A:Dg5 2.99 Pt C4 A:Dg5 4.15 Pt H8 A:Dg5 3.18 Pt N1 A:Dg5 4.83 Pt N7 A:Dg5 1.96 Pt O6 A:Dg5 3.31 Pt H72 A:Dt6 4.42 Pt H71 A:Dt6 4.83 Pt C4 A:Dt6 4.99 Pt O4 A:Dt6 4.38 Pt H41 B:Dc12 4.44 Pt N1 A:Cpt17 2.00 Pt N2 A:Cpt17 1.99 Pt H13 A:Cpt17 2.56 Pt PT1 A:Cpt17 0.00 Pt H23 A:Cpt17 2.52 Pt H21 A:Cpt17 2.54 Pt H22 A:Cpt17 2.57 Pt H11 A:Cpt17 2.53 Pt H12 A:Cpt17 2.54 interactive model: