Platinum in PDB 1au6: Solution Structure of Dna D(Catgcatg) Interstrand- Crosslinked By Bisplatin Compound (1,1/T,T), uc(Nmr), Minimized Average Structure

The binding sites of Platinum atom in the Solution Structure of Dna D(Catgcatg) Interstrand- Crosslinked By Bisplatin Compound (1,1/T,T), uc(Nmr), Minimized Average Structure (pdb code 1au6). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total 2 binding sites of Platinum where determined in the Solution Structure of Dna D(Catgcatg) Interstrand- Crosslinked By Bisplatin Compound (1,1/T,T), uc(Nmr), Minimized Average Structure, PDB code: 1au6:
Jump to Platinum binding site number: 1; 2;

Platinum binding site 1 out of 2 in the Solution Structure of Dna D(Catgcatg) Interstrand- Crosslinked By Bisplatin Compound (1,1/T,T), uc(Nmr), Minimized Average Structure


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Solution Structure of Dna D(Catgcatg) Interstrand- Crosslinked By Bisplatin Compound (1,1/T,T), uc(Nmr), Minimized Average Structure within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt17 b:0.0 occ:1.00 PT1 A:BPT17 0.0 0.0 1.0 N7 A:DG4 2.0 0.0 1.0 N1 A:BPT17 2.0 0.0 1.0 N3 A:BPT17 2.0 0.0 1.0 N4 A:BPT17 2.0 0.0 1.0 HN11 A:BPT17 2.5 0.0 1.0 HN31 A:BPT17 2.5 0.0 1.0 HN41 A:BPT17 2.5 0.0 1.0 HN12 A:BPT17 2.6 0.0 1.0 HN42 A:BPT17 2.6 0.0 1.0 HN43 A:BPT17 2.6 0.0 1.0 HN32 A:BPT17 2.6 0.0 1.0 HN33 A:BPT17 2.6 0.0 1.0 HC12 A:BPT17 2.8 0.0 1.0 C1 A:BPT17 2.9 0.0 1.0 H4' A:DT3 2.9 0.0 1.0 C8 A:DG4 3.0 0.0 1.0 C5 A:DG4 3.0 0.0 1.0 HC11 A:BPT17 3.1 0.0 1.0 H8 A:DG4 3.4 0.0 1.0 O6 A:DG4 3.5 0.0 1.0 C6 A:DG4 3.6 0.0 1.0 OP1 A:DT3 3.6 0.0 1.0 C4' A:DT3 3.9 0.0 1.0 O3' A:DA2 4.0 0.0 1.0 O3' A:DT3 4.0 0.0 1.0 H4' B:DC9 4.1 0.0 1.0 N9 A:DG4 4.2 0.0 1.0 C4 A:DG4 4.2 0.0 1.0 C2 A:BPT17 4.2 0.0 1.0 O4' A:DT3 4.3 0.0 1.0 H1' A:DT3 4.3 0.0 1.0 HC22 A:BPT17 4.4 0.0 1.0 P A:DT3 4.4 0.0 1.0 HC21 A:BPT17 4.5 0.0 1.0 H5' B:DA10 4.5 0.0 1.0 H1' A:DA2 4.6 0.0 1.0 C3' A:DT3 4.6 0.0 1.0 H5' A:DT3 4.6 0.0 1.0 C5' A:DT3 4.8 0.0 1.0 H5'' B:DC9 4.9 0.0 1.0 C1' A:DT3 4.9 0.0 1.0 N1 A:DG4 4.9 0.0 1.0

Platinum binding site 2 out of 2 in the Solution Structure of Dna D(Catgcatg) Interstrand- Crosslinked By Bisplatin Compound (1,1/T,T), uc(Nmr), Minimized Average Structure


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 2 of Solution Structure of Dna D(Catgcatg) Interstrand- Crosslinked By Bisplatin Compound (1,1/T,T), uc(Nmr), Minimized Average Structure within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt17 b:0.0 occ:1.00 PT2 A:BPT17 0.0 0.0 1.0 N7 B:DG12 2.0 0.0 1.0 N2 A:BPT17 2.0 0.0 1.0 N5 A:BPT17 2.0 0.0 1.0 N6 A:BPT17 2.0 0.0 1.0 HN21 A:BPT17 2.5 0.0 1.0 HN51 A:BPT17 2.5 0.0 1.0 HN61 A:BPT17 2.5 0.0 1.0 HN22 A:BPT17 2.6 0.0 1.0 HN62 A:BPT17 2.6 0.0 1.0 HN63 A:BPT17 2.6 0.0 1.0 HN52 A:BPT17 2.6 0.0 1.0 HN53 A:BPT17 2.6 0.0 1.0 HC42 A:BPT17 2.9 0.0 1.0 C4 A:BPT17 2.9 0.0 1.0 H4' B:DT11 2.9 0.0 1.0 C8 B:DG12 3.0 0.0 1.0 C5 B:DG12 3.0 0.0 1.0 HC41 A:BPT17 3.0 0.0 1.0 H8 B:DG12 3.4 0.0 1.0 O6 B:DG12 3.5 0.0 1.0 C6 B:DG12 3.6 0.0 1.0 OP1 B:DT11 3.6 0.0 1.0 C4' B:DT11 3.9 0.0 1.0 O3' B:DA10 4.0 0.0 1.0 O3' B:DT11 4.0 0.0 1.0 H4' A:DC1 4.2 0.0 1.0 N9 B:DG12 4.2 0.0 1.0 C4 B:DG12 4.2 0.0 1.0 C3 A:BPT17 4.2 0.0 1.0 O4' B:DT11 4.3 0.0 1.0 H1' B:DT11 4.3 0.0 1.0 HC32 A:BPT17 4.4 0.0 1.0 P B:DT11 4.4 0.0 1.0 HC31 A:BPT17 4.5 0.0 1.0 H5' A:DA2 4.6 0.0 1.0 H1' B:DA10 4.6 0.0 1.0 C3' B:DT11 4.6 0.0 1.0 H5' B:DT11 4.6 0.0 1.0 C5' B:DT11 4.8 0.0 1.0 H5'' A:DC1 4.9 0.0 1.0 C1' B:DT11 4.9 0.0 1.0 N1 B:DG12 4.9 0.0 1.0

D.Yang, S.S.Van Boom, J.Reedijk, J.H.Van Boom, N.Farrell, A.H.Wang. A Novel Dna Structure Induced By the Anticancer Bisplatinum Compound Crosslinked to A Gpc Site in Dna. Nat.Struct.Biol. V. 2 577 1995.
ISSN: ISSN 1072-8368
PubMed: 7664126
DOI: 10.1038/NSB0795-577