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Platinum in PDB 1bix: The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites

Enzymatic activity of The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites

All present enzymatic activity of The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites:
4.2.99.18;

Protein crystallography data

The structure of The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites, PDB code: 1bix was solved by M.A.Gorman, S.Morera, D.G.Rothwell, E.De La Fortelle, C.D.Mol, J.A.Tainer, I.D.Hickson, P.S.Freemont, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.20
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 87.260, 44.701, 78.778, 90.00, 103.45, 90.00
R / Rfree (%) 18.4 / 26.9

Other elements in 1bix:

The structure of The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites also contains other interesting chemical elements:

Samarium (Sm) 4 atoms

Platinum Binding Sites:

The binding sites of Platinum atom in the The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites (pdb code 1bix). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites, PDB code: 1bix:

Platinum binding site 1 out of 1 in 1bix

Go back to Platinum Binding Sites List in 1bix
Platinum binding site 1 out of 1 in the The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt404

b:65.3
occ:0.40
SD A:MET271 2.0 51.7 1.0
CG A:MET271 2.8 50.2 1.0
NZ A:LYS276 2.9 32.6 1.0
CE A:MET271 3.3 51.1 1.0
CE A:LYS276 3.4 30.4 1.0
CB A:MET271 3.5 46.6 1.0
O A:MET271 4.0 43.8 1.0
CD A:LYS276 4.6 30.0 1.0
CA A:MET271 4.7 43.7 1.0
C A:MET271 4.8 43.4 1.0

Reference:

M.A.Gorman, S.Morera, D.G.Rothwell, E.De La Fortelle, C.D.Mol, J.A.Tainer, I.D.Hickson, P.S.Freemont. The Crystal Structure of the Human Dna Repair Endonuclease HAP1 Suggests the Recognition of Extra-Helical Deoxyribose at Dna Abasic Sites. Embo J. V. 16 6548 1997.
ISSN: ISSN 0261-4189
PubMed: 9351835
DOI: 10.1093/EMBOJ/16.21.6548
Page generated: Wed Dec 16 02:03:33 2020

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