Platinum in the structure of Crystal Structure of HMG1 Domain A Bound to A Cisplatin-Modified Dna Duplex (pdb 1ckt)

The binding sites of Platinum atom in the structure of Crystal Structure of HMG1 Domain A Bound to A Cisplatin-Modified Dna Duplex (pdb code 1ckt). This binding sites where shown with 5.0 Angstroms radius around Platinum atom. The 1ckt structure was solved by U.-M.OHNDORF, M.A.ROULD, C.O.PABO, S.J.LIPPARD, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 100.0-2.5 Space group C121 a (A) 105.210 b (A) 50.410 c (A) 53.130 alpha (°) 90.00 beta (°) 99.82 gamma (°) 90.00 Rfactor (%) 23.8 Rfree (%) 23.9 Platinum Binding Sites: Platinum binding site 1 out of 1 in 1ckt Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Platinum in the PDB 1ckt. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Dg108, B: Dg109, B: Cpt99, B: Hoh305, B: Hoh334, B: Hoh374, C: Hoh311, conact list: Atom Atom Distance (A) Pt N9 B:Dg108 3.93 Pt C8 B:Dg108 2.64 Pt C6 B:Dg108 3.95 Pt C5 B:Dg108 3.18 Pt N7 B:Dg108 1.94 Pt C4 B:Dg108 4.18 Pt OP2 B:Dg108 4.37 Pt O6 B:Dg108 3.95 Pt N9 B:Dg109 4.00 Pt C8 B:Dg109 2.73 Pt C6 B:Dg109 3.75 Pt C5 B:Dg109 3.08 Pt N7 B:Dg109 1.89 Pt C4 B:Dg109 4.16 Pt O6 B:Dg109 3.67 Pt N1 B:Cpt99 1.96 Pt N2 B:Cpt99 1.98 Pt PT1 B:Cpt99 0.00 Pt O B:Hoh305 4.55 Pt O B:Hoh334 4.53 Pt O B:Hoh374 3.97 Pt O C:Hoh311 4.50 interactive model: