Platinum in PDB 1gwb: Structure of Glycoprotein 1B

The structure of Structure of Glycoprotein 1B, PDB code: 1gwb was solved by J.Emsley, S.Uff, K.J.M.Clemetson, J.M.Clemetson, T.Harrison, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 2.80
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	202.000, 202.000, 128.000, 90.00, 90.00, 120.00
R / Rfree (%)	24.5 / 27.4

The binding sites of Platinum atom in the Structure of Glycoprotein 1B (pdb code 1gwb). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total 4 binding sites of Platinum where determined in the Structure of Glycoprotein 1B, PDB code: 1gwb:
Jump to Platinum binding site number: 1; 2; 3; 4;

Platinum binding site 1 out of 4 in the Structure of Glycoprotein 1B


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Structure of Glycoprotein 1B within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt301 b:0.5 occ:1.00 CG2 A:THR91 3.2 75.2 1.0 OG1 A:THR91 3.4 77.8 1.0 CB A:MET68 3.5 64.6 1.0 CB A:THR91 3.9 76.2 1.0 CA A:MET68 4.6 66.0 1.0 O A:MET68 4.9 67.4 1.0 C A:MET68 4.9 67.4 1.0

Platinum binding site 2 out of 4 in the Structure of Glycoprotein 1B


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 2 of Structure of Glycoprotein 1B within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt302 b:98.6 occ:1.00 O A:VAL250 3.6 85.0 1.0 CG2 A:VAL252 3.7 85.8 1.0 N A:VAL252 4.1 86.6 1.0 CB A:MET255 4.1 70.2 1.0 CA A:VAL252 4.3 86.1 1.0 C A:ASP251 4.4 86.5 1.0 C A:VAL250 4.5 84.3 1.0 CB A:VAL252 4.6 86.3 1.0 CA A:ASP251 4.9 86.9 1.0 CZ3 A:TRP246 4.9 55.3 1.0 O A:ASP251 4.9 86.5 1.0 CZ A:PHE217 5.0 38.9 1.0 CE3 A:TRP246 5.0 55.0 1.0

Platinum binding site 3 out of 4 in the Structure of Glycoprotein 1B


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 3 of Structure of Glycoprotein 1B within 5.0Å range: probe atom residue distance (Å) B Occ B:Pt301 b:0.7 occ:1.00 O B:HOH468 2.7 28.8 1.0 CB B:MET255 4.0 82.1 1.0 O B:VAL250 4.1 0.8 1.0 O B:HOH480 4.2 38.7 1.0 O B:ASP251 4.2 1.0 1.0 CA B:VAL252 4.4 0.7 1.0 C B:ASP251 4.4 0.6 1.0 N B:VAL252 4.5 1.0 1.0 O B:HOH479 4.7 19.0 1.0 C B:VAL250 4.9 0.2 1.0 CB B:VAL252 4.9 0.9 1.0 CZ B:PHE217 5.0 37.8 1.0 N B:LYS247 5.0 66.5 1.0

Platinum binding site 4 out of 4 in the Structure of Glycoprotein 1B


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 4 of Structure of Glycoprotein 1B within 5.0Å range: probe atom residue distance (Å) B Occ B:Pt302 b:0.5 occ:1.00 O B:HOH476 3.0 43.9 1.0 O B:HOH481 3.2 10.3 1.0 CB B:MET68 4.0 48.3 1.0 CD B:PRO69 4.7 47.2 1.0 N B:PRO69 4.8 48.7 1.0 C B:MET68 5.0 49.3 1.0

S.Uff, J.M.Clemetson, T.Harrison, K.J.Clemetson, J.Emsley. Crystal Structure of the Platelet Glycoprotein Ib-Alpha N-Terminal Domain Reveals An Unmasking Mechanism of Receptor Activation J.Biol.Chem. V. 277 35657 2002.
ISSN: ISSN 0021-9258
PubMed: 12087105
DOI: 10.1074/JBC.M205271200