Platinum in the structure of Relationship Of Solution and Protein-Bound Structures of Dna Duplexes With the Major Intrastrand Cross-Link Lesions Formed on Cisplatin Binding to Dna (pdb 1ksb)

The binding sites of Platinum atom in the structure of Relationship Of Solution and Protein-Bound Structures of Dna Duplexes With the Major Intrastrand Cross-Link Lesions Formed on Cisplatin Binding to Dna (pdb code 1ksb). This binding sites where shown with 5.0 Angstroms radius around Platinum atom. The 1ksb structure was solved by L.G.MARZILLI, J.S.SAAD, Z.KUKLENYIK, K.A.KEATING, Y.XU, with NMR in Solution technique. Platinum Binding Sites: Platinum binding site 1 out of 1 in 1ksb Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Platinum in the PDB 1ksb. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Dc4, A: Dg5, A: Dg6, A: Dc7, A: Cpt10, conact list: Atom Atom Distance (A) Pt H2' A:Dc4 4.43 Pt N9 A:Dg5 4.03 Pt C8 A:Dg5 2.82 Pt C6 A:Dg5 3.90 Pt C5 A:Dg5 3.20 Pt C4 A:Dg5 4.23 Pt H8 A:Dg5 2.96 Pt N7 A:Dg5 2.01 Pt OP2 A:Dg5 4.42 Pt H2' A:Dg5 4.69 Pt O6 A:Dg5 3.82 Pt N9 A:Dg6 4.19 Pt C8 A:Dg6 3.00 Pt C6 A:Dg6 3.63 Pt C5 A:Dg6 3.09 Pt C4 A:Dg6 4.24 Pt H8 A:Dg6 3.32 Pt N7 A:Dg6 2.01 Pt O6 A:Dg6 3.42 Pt H42 A:Dc7 4.37 Pt H41 A:Dc7 4.95 Pt N4 A:Dc7 4.89 Pt N1 A:Cpt10 2.03 Pt N2 A:Cpt10 2.03 Pt H13 A:Cpt10 2.55 Pt PT1 A:Cpt10 0.00 Pt H23 A:Cpt10 2.55 Pt H21 A:Cpt10 2.55 Pt H22 A:Cpt10 2.55 Pt H11 A:Cpt10 2.55 Pt H12 A:Cpt10 2.55 interactive model: