Platinum in the structure of uc(Nmr) Solution Structure of An Oxaliplatin 1,2-D(Gg) Intrastrand Cross-Link in A Dna Dodecamer Duplex (pdb 1pg9)

The binding sites of Platinum atom in the structure of uc(Nmr) Solution Structure of An Oxaliplatin 1,2-D(Gg) Intrastrand Cross-Link in A Dna Dodecamer Duplex (pdb code 1pg9). This binding sites where shown with 5.0 Angstroms radius around Platinum atom. The 1pg9 structure was solved by Y.WU, P.PRADHAN, J.HAVENER, S.G.CHANEY, S.L.CAMPBEL, with NMR in Solution technique. Platinum Binding Sites: Platinum binding site 1 out of 1 in 1pg9 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Platinum in the PDB 1pg9. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Da5, A: Dg6, A: Dg7, A: 1pt77, conact list: Atom Atom Distance (A) Pt N7 A:Da5 4.93 Pt N9 A:Dg6 3.95 Pt C8 A:Dg6 2.87 Pt C6 A:Dg6 3.48 Pt C5 A:Dg6 2.92 Pt C4 A:Dg6 3.98 Pt H8 A:Dg6 3.14 Pt N1 A:Dg6 4.76 Pt N7 A:Dg6 2.01 Pt H2' A:Dg6 4.84 Pt O6 A:Dg6 3.43 Pt N9 A:Dg7 4.18 Pt C8 A:Dg7 2.99 Pt C6 A:Dg7 3.56 Pt C5 A:Dg7 3.05 Pt C4 A:Dg7 4.22 Pt H8 A:Dg7 3.21 Pt N1 A:Dg7 4.93 Pt N7 A:Dg7 2.01 Pt O6 A:Dg7 3.37 Pt N2 A:1pt77 2.02 Pt C1 A:1pt77 2.91 Pt H21 A:1pt77 2.57 Pt H11 A:1pt77 2.58 Pt PT A:1pt77 0.00 Pt H61 A:1pt77 4.47 Pt H32 A:1pt77 4.47 Pt H12 A:1pt77 2.57 Pt C2 A:1pt77 2.90 Pt N1 A:1pt77 2.03 Pt H62 A:1pt77 4.69 Pt C6 A:1pt77 4.27 Pt H1 A:1pt77 3.21 Pt H31 A:1pt77 4.70 Pt H2 A:1pt77 3.20 Pt H22 A:1pt77 2.57 Pt C3 A:1pt77 4.28 interactive model: