Platinum in the structure of Solution Structures of A Dna Dodecamer Duplex With A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link (pdb 2npw)

The binding sites of Platinum atom in the structure of Solution Structures of A Dna Dodecamer Duplex With A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link (pdb code 2npw). This binding sites where shown with 5.0 Angstroms radius around Platinum atom. The 2npw structure was solved by Y.WU, D.BHATTACHARYYA, S.CHANEY, S.CAMPBELL, with NMR in Solution technique. Platinum Binding Sites: Platinum binding site 1 out of 1 in 2npw Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Platinum in the PDB 2npw. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Da5, A: Dg6, A: Dg7, A: Dc8, A: Cpt77, conact list: Atom Atom Distance (A) Pt N7 A:Da5 4.81 Pt N9 A:Dg6 3.97 Pt C8 A:Dg6 2.89 Pt C6 A:Dg6 3.46 Pt C5 A:Dg6 2.92 Pt C4 A:Dg6 3.99 Pt H8 A:Dg6 3.17 Pt N1 A:Dg6 4.74 Pt N7 A:Dg6 2.01 Pt H2' A:Dg6 4.88 Pt O6 A:Dg6 3.40 Pt N9 A:Dg7 4.19 Pt C8 A:Dg7 2.99 Pt C6 A:Dg7 3.58 Pt C5 A:Dg7 3.06 Pt C4 A:Dg7 4.23 Pt H8 A:Dg7 3.20 Pt N1 A:Dg7 4.95 Pt N7 A:Dg7 2.01 Pt O6 A:Dg7 3.39 Pt H42 A:Dc8 4.91 Pt N1 A:Cpt77 2.03 Pt N2 A:Cpt77 2.03 Pt H13 A:Cpt77 2.55 Pt PT1 A:Cpt77 0.00 Pt H23 A:Cpt77 2.55 Pt H21 A:Cpt77 2.55 Pt H22 A:Cpt77 2.55 Pt H11 A:Cpt77 2.55 Pt H12 A:Cpt77 2.55 interactive model: