Platinum in PDB 2npw: Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link

The binding sites of Platinum atom in the Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link (pdb code 2npw). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link, PDB code: 2npw:

Platinum binding site 1 out of 1 in the Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt77 b:0.6 occ:1.00 PT1 A:CPT77 0.0 0.6 1.0 N7 A:DG6 2.0 0.6 1.0 N7 A:DG7 2.0 0.5 1.0 N2 A:CPT77 2.0 0.6 1.0 N1 A:CPT77 2.0 0.7 1.0 H23 A:CPT77 2.6 0.9 1.0 H22 A:CPT77 2.6 1.2 1.0 H21 A:CPT77 2.6 1.2 1.0 H13 A:CPT77 2.6 1.1 1.0 H12 A:CPT77 2.6 1.2 1.0 H11 A:CPT77 2.6 1.0 1.0 C8 A:DG6 2.9 0.7 1.0 C5 A:DG6 2.9 0.6 1.0 C8 A:DG7 3.0 0.5 1.0 C5 A:DG7 3.1 0.5 1.0 H8 A:DG6 3.2 0.7 1.0 H8 A:DG7 3.2 0.5 1.0 O6 A:DG7 3.4 0.5 1.0 O6 A:DG6 3.4 0.6 1.0 C6 A:DG6 3.5 0.6 1.0 C6 A:DG7 3.6 0.5 1.0 N9 A:DG6 4.0 0.7 1.0 C4 A:DG6 4.0 0.7 1.0 N9 A:DG7 4.2 0.5 1.0 C4 A:DG7 4.2 0.5 1.0 N1 A:DG6 4.7 0.6 1.0 N7 A:DA5 4.8 0.6 1.0 H2' A:DG6 4.9 0.8 1.0 H42 A:DC8 4.9 0.6 1.0 N1 A:DG7 4.9 0.5 1.0

Y.Wu, D.Bhattacharyya, C.L.King, I.Baskerville-Abraham, S.-H.Huh, G.Boysen, J.A.Swenberg, B.Temple, S.L.Campbell, S.G.Chaney. Solution Structures of A Dna Dodecamer Duplex with and Without A Cisplatin 1,2-D(Gg) Intrastrand Cross-Link: Comparison with the Same Dna Duplex Containing An Oxaliplatin 1,2-D(Gg) Intrastrand Cross-Link Biochemistry V. 46 6477 2007.
ISSN: ISSN 0006-2960
PubMed: 17497831
DOI: 10.1021/BI062291F