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Platinum in PDB 2nq0: Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link

Platinum Binding Sites:

The binding sites of Platinum atom in the Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link (pdb code 2nq0). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link, PDB code: 2nq0:

Platinum binding site 1 out of 1 in 2nq0

Go back to Platinum Binding Sites List in 2nq0
Platinum binding site 1 out of 1 in the Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Solution Structures of A Dna Dodecamer Duplex with A Cisplatin 1,2- D(Gg) Intrastrand Cross-Link within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt77

b:0.5
occ:1.00
PT1 A:CPT77 0.0 0.5 1.0
N7 A:DG6 2.0 0.6 1.0
N7 A:DG7 2.0 0.4 1.0
N2 A:CPT77 2.0 0.5 1.0
N1 A:CPT77 2.0 0.6 1.0
H23 A:CPT77 2.6 1.1 1.0
H12 A:CPT77 2.6 1.3 1.0
H21 A:CPT77 2.6 1.0 1.0
H22 A:CPT77 2.6 1.1 1.0
H13 A:CPT77 2.6 1.0 1.0
H11 A:CPT77 2.6 1.1 1.0
C8 A:DG6 2.9 0.6 1.0
C5 A:DG6 2.9 0.6 1.0
C8 A:DG7 3.0 0.4 1.0
C5 A:DG7 3.1 0.4 1.0
H8 A:DG7 3.2 0.4 1.0
H8 A:DG6 3.2 0.7 1.0
O6 A:DG6 3.4 0.5 1.0
O6 A:DG7 3.4 0.4 1.0
C6 A:DG6 3.4 0.5 1.0
C6 A:DG7 3.6 0.4 1.0
N9 A:DG6 4.0 0.6 1.0
C4 A:DG6 4.0 0.6 1.0
N9 A:DG7 4.2 0.4 1.0
C4 A:DG7 4.2 0.4 1.0
N7 A:DA5 4.6 0.5 1.0
N1 A:DG6 4.7 0.5 1.0
C5 A:DA5 4.8 0.5 1.0
H42 A:DC8 4.9 0.4 1.0
H2' A:DG6 4.9 0.7 1.0
C8 A:DA5 4.9 0.5 1.0
H41 B:DC19 5.0 0.5 1.0
N1 A:DG7 5.0 0.4 1.0

Reference:

Y.Wu, D.Bhattacharyya, C.L.King, I.Baskerville-Abraham, S.-H.Huh, G.Boysen, J.A.Swenberg, B.Temple, S.L.Campbell, S.G.Chaney. Solution Structures of A Dna Dodecamer Duplex with and Without A Cisplatin 1,2-D(Gg) Intrastrand Cross-Link: Comparison with the Same Dna Duplex Containing An Oxaliplatin 1,2-D(Gg) Intrastrand Cross-Link Biochemistry V. 46 6477 2007.
ISSN: ISSN 0006-2960
PubMed: 17497831
DOI: 10.1021/BI062291F
Page generated: Wed Dec 16 02:04:03 2020

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