Platinum in the structure of Crystal Structure of Human Thioredoxin Reductase I and Terpyridine Platinum(II) (pdb 2zzb)

The binding sites of Platinum atom in the structure of Crystal Structure of Human Thioredoxin Reductase I and Terpyridine Platinum(II) (pdb code 2zzb). This binding sites where shown with 5.0 Angstroms radius around Platinum atom. The 2zzb structure was solved by Y.C.LO, T.P.KO, A.H.J.WANG, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 30.0-3.2 Space group C2221 a (A) 120.947 b (A) 135.165 c (A) 346.037 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 24.2 Rfree (%) 30.5 Platinum Binding Sites: Platinum binding site 1 out of 2 in 2zzb Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Platinum in the PDB 2zzb. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Ser111, B: Trp114, B: Tpt501, conact list: Atom Atom Distance (A) Pt CA B:Ser111 4.78 Pt CB B:Trp114 4.08 Pt CD1 B:Trp114 4.86 Pt CG B:Trp114 4.62 Pt C9 B:Tpt501 4.23 Pt N3 B:Tpt501 2.03 Pt C12 B:Tpt501 4.22 Pt N2 B:Tpt501 1.98 Pt C11 B:Tpt501 2.89 Pt C1 B:Tpt501 3.03 Pt C14 B:Tpt501 4.33 Pt C8 B:Tpt501 4.75 Pt C2 B:Tpt501 4.33 Pt C6 B:Tpt501 2.94 Pt N1 B:Tpt501 2.06 Pt C5 B:Tpt501 2.93 Pt C7 B:Tpt501 4.25 Pt PT1 B:Tpt501 0.00 Pt C4 B:Tpt501 4.26 Pt C13 B:Tpt501 4.79 Pt C10 B:Tpt501 2.91 Pt C3 B:Tpt501 4.82 Pt C15 B:Tpt501 3.01 interactive model: Platinum binding site 2 out of 2 in 2zzb Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Platinum in the PDB 2zzb. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: Cys498, D: Ser111, D: Trp114, D: Tpt501, conact list: Atom Atom Distance (A) Pt CB C:Cys498 3.51 Pt SG C:Cys498 2.24 Pt CA C:Cys498 4.74 Pt CA D:Ser111 4.94 Pt CB D:Trp114 4.33 Pt CG D:Trp114 4.92 Pt C9 D:Tpt501 4.23 Pt N3 D:Tpt501 2.03 Pt C12 D:Tpt501 4.22 Pt N2 D:Tpt501 1.99 Pt C11 D:Tpt501 2.90 Pt C1 D:Tpt501 3.04 Pt C14 D:Tpt501 4.33 Pt C8 D:Tpt501 4.76 Pt C2 D:Tpt501 4.33 Pt C6 D:Tpt501 2.95 Pt N1 D:Tpt501 2.06 Pt C5 D:Tpt501 2.93 Pt C7 D:Tpt501 4.25 Pt PT1 D:Tpt501 0.00 Pt C4 D:Tpt501 4.27 Pt C13 D:Tpt501 4.79 Pt C10 D:Tpt501 2.91 Pt C3 D:Tpt501 4.82 Pt C15 D:Tpt501 3.01 interactive model: