Platinum in the structure of Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Dimer) (pdb 3iwx)

The binding sites of Platinum atom in the structure of Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Dimer) (pdb code 3iwx). This binding sites where shown with 5.0 Angstroms radius around Platinum atom. The 3iwx structure was solved by A.K.BOAL, A.C.ROSENZWEIG, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 28.8-2.1 Space group P65 a (A) 78.289 b (A) 78.289 c (A) 54.335 alpha (°) 90.00 beta (°) 90.00 gamma (°) 120.00 Rfactor (%) 18.6 Rfree (%) 22.8 Platinum Binding Sites: Platinum binding site 1 out of 1 in 3iwx Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Platinum in the PDB 3iwx. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Thr11, A: Cys12, A: Gly14, A: Cys15, B: Thr11, B: Cys12, B: Gly14, B: Cys15, A: Cpt69, B: Hoh134, conact list: Atom Atom Distance (A) Pt OG1 A:Thr11 4.47 Pt C A:Thr11 4.74 Pt O A:Cys12 4.66 Pt N A:Cys12 4.14 Pt CB A:Cys12 3.57 Pt SG A:Cys12 2.48 Pt C A:Cys12 4.70 Pt CA A:Cys12 4.32 Pt N A:Gly14 4.97 Pt C A:Gly14 4.51 Pt CA A:Gly14 4.81 Pt N A:Cys15 3.64 Pt CB A:Cys15 3.62 Pt SG A:Cys15 2.31 Pt CA A:Cys15 4.04 Pt N B:Thr11 4.90 Pt OG1 B:Thr11 4.30 Pt C B:Thr11 4.85 Pt O B:Cys12 4.47 Pt N B:Cys12 3.88 Pt CB B:Cys12 3.65 Pt SG B:Cys12 2.46 Pt C B:Cys12 4.54 Pt CA B:Cys12 4.19 Pt N B:Gly14 4.85 Pt C B:Gly14 4.31 Pt CA B:Gly14 4.64 Pt N B:Cys15 3.53 Pt CB B:Cys15 3.51 Pt SG B:Cys15 2.10 Pt CA B:Cys15 3.93 Pt N1 A:Cpt69 1.99 Pt N2 A:Cpt69 1.80 Pt PT1 A:Cpt69 0.00 Pt O B:Hoh134 4.28 interactive model: