Platinum in the structure of The Crystal Structure of Human Ubiquitin Adduct With Zeise'S Salt (pdb 3n32)

The binding sites of Platinum atom in the structure of The Crystal Structure of Human Ubiquitin Adduct With Zeise'S Salt (pdb code 3n32). This binding sites where shown with 5.0 Angstroms radius around Platinum atom. The 3n32 structure was solved by D.SILIQI, R.CALIANDRO, G.FALINI, S.FERMANI, G.NATILE, F.ARNESANO, B.D.BELVISO, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 25.1-1.8 Space group P212121 a (A) 29.060 b (A) 40.450 c (A) 49.760 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 18.1 Rfree (%) 25.8 Platinum Binding Sites: Platinum binding site 1 out of 3 in 3n32 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Platinum in the PDB 3n32. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Lys6, A: Thr66, A: His68, A: Hoh207, A: Hoh214, A: Hoh220, A: Hoh259, conact list: Atom Atom Distance (A) Pt CE A:Lys6 4.63 Pt NZ A:Lys6 4.55 Pt CB A:Thr66 4.98 Pt CG2 A:Thr66 4.44 Pt NE2 A:His68 2.37 Pt ND1 A:His68 4.51 Pt CD2 A:His68 2.99 Pt CE1 A:His68 3.56 Pt CG A:His68 4.27 Pt O A:Hoh207 4.81 Pt O A:Hoh214 2.73 Pt O A:Hoh220 2.37 Pt O A:Hoh259 4.10 interactive model: Platinum binding site 2 out of 3 in 3n32 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Platinum in the PDB 3n32. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Met1, A: Gln2, A: Glu16, A: Val17, A: Hoh201, A: Hoh234, A: Hoh239, conact list: Atom Atom Distance (A) Pt O A:Met1 4.05 Pt N A:Met1 2.15 Pt CB A:Met1 4.50 Pt C A:Met1 3.84 Pt CA A:Met1 3.41 Pt N A:Gln2 4.58 Pt CB A:Glu16 4.43 Pt CD A:Glu16 4.81 Pt CG A:Glu16 4.82 Pt CA A:Glu16 4.90 Pt O A:Val17 4.05 Pt N A:Val17 4.65 Pt C A:Val17 5.00 Pt O A:Hoh201 2.46 Pt O A:Hoh234 2.47 Pt O A:Hoh239 4.20 interactive model: Platinum binding site 3 out of 3 in 3n32 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Platinum in the PDB 3n32. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Platinum atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Lys6, A: Gly10, A: Hoh209, A: Hoh220, A: Hoh222, A: Hoh236, conact list: Atom Atom Distance (A) Pt CE A:Lys6 3.19 Pt CD A:Lys6 4.31 Pt NZ A:Lys6 2.55 Pt CA A:Gly10 4.96 Pt O A:Hoh209 4.50 Pt O A:Hoh220 4.83 Pt O A:Hoh222 2.67 Pt O A:Hoh236 2.70 interactive model: