Platinum in PDB 3txi: Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant

All present enzymatic activity of Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant:
3.2.1.17;

The structure of Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant, PDB code: 3txi was solved by S.W.M.Tanley, A.M.M.Schreurs, J.R.Helliwell, L.M.J.Kroon-Batenburg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	55.17 / 1.60
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	78.023, 78.023, 36.970, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 23.3

The structure of Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant also contains other interesting chemical elements:

Chlorine	(Cl)	8 atoms
Sodium	(Na)	1 atom

The binding sites of Platinum atom in the Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant (pdb code 3txi). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total 2 binding sites of Platinum where determined in the Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant, PDB code: 3txi:
Jump to Platinum binding site number: 1; 2;

Platinum binding site 1 out of 2 in the Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt130 b:41.4 occ:1.00 PT1 A:QPT130 0.0 41.4 1.0 N1 A:QPT130 2.1 39.5 1.0 N2 A:QPT130 2.1 30.3 1.0 NH1 A:ARG14 2.2 32.8 1.0 NE2 A:HIS15 2.4 31.4 1.0 CL A:CL1133 2.6 35.2 1.0 CE1 A:HIS15 3.3 32.4 1.0 CD2 A:HIS15 3.4 30.7 1.0 CZ A:ARG14 3.5 35.7 1.0 CD A:ARG14 4.2 34.2 1.0 NE A:ARG14 4.2 43.5 1.0 OD1 A:ASP87 4.3 35.3 1.0 NH2 A:ARG14 4.3 44.8 1.0 ND1 A:HIS15 4.4 31.8 1.0 CG A:HIS15 4.5 30.0 1.0 O A:HOH2015 4.5 29.4 1.0 CG A:ASP87 4.7 36.9 1.0 CB A:ALA11 4.7 25.1 1.0 N A:ILE88 4.8 26.5 1.0 OD2 A:ASP87 4.9 42.2 1.0 OG1 A:THR89 4.9 30.5 1.0 CG1 A:ILE88 5.0 26.9 1.0

Platinum binding site 2 out of 2 in the Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 2 of Hewl Co-Crystallization with Carboplatin in Dmso Media with Paratone As the Cryoprotectant within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt131 b:46.3 occ:1.00 PT1 A:QPT131 0.0 46.3 1.0 N1 A:QPT131 2.1 43.0 1.0 N2 A:QPT131 2.1 40.6 1.0 ND1 A:HIS15 2.3 31.8 1.0 O A:HOH2105 2.5 20.7 1.0 CE1 A:HIS15 3.3 32.4 1.0 CG A:HIS15 3.3 30.0 1.0 CB A:HIS15 3.6 28.8 1.0 CA A:HIS15 3.6 29.4 1.0 O A:HIS15 4.1 30.2 1.0 O A:HOH2101 4.2 32.2 1.0 C A:HIS15 4.3 29.2 1.0 NE2 A:HIS15 4.4 31.4 1.0 CD2 A:HIS15 4.4 30.7 1.0 OG1 A:THR89 4.6 30.5 1.0 CG2 A:THR89 4.6 30.6 1.0 N A:HIS15 4.6 28.5 1.0 O A:ARG14 4.8 30.8 1.0 C2 A:DMS134 4.9 50.5 1.0

S.W.Tanley, A.M.Schreurs, J.R.Helliwell, L.M.Kroon-Batenburg. Experience with Exchange and Archiving of Raw Data: Comparison of Data From Two Diffractometers and Four Software Packages on A Series of Lysozyme Crystals. J.Appl.Crystallogr. V. 46 108 2013.
ISSN: ISSN 0021-8898
PubMed: 23396873
DOI: 10.1107/S0021889812044172