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Atomistry » Platinum » PDB 3wua-4nsi » 4dl7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Platinum » PDB 3wua-4nsi » 4dl7 » |
Platinum in PDB 4dl7: Human Dna Polymerase Eta Fails to Extend Primer 2 Nucleotide After Cisplatin Crosslink (Pt-GG4).Enzymatic activity of Human Dna Polymerase Eta Fails to Extend Primer 2 Nucleotide After Cisplatin Crosslink (Pt-GG4).
All present enzymatic activity of Human Dna Polymerase Eta Fails to Extend Primer 2 Nucleotide After Cisplatin Crosslink (Pt-GG4).:
2.7.7.7; Protein crystallography data
The structure of Human Dna Polymerase Eta Fails to Extend Primer 2 Nucleotide After Cisplatin Crosslink (Pt-GG4)., PDB code: 4dl7
was solved by
Y.Zhao,
C.Biertumpfel,
M.Gregory,
Y.Hua,
F.Hanaoka,
W.Yang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Platinum Binding Sites:
The binding sites of Platinum atom in the Human Dna Polymerase Eta Fails to Extend Primer 2 Nucleotide After Cisplatin Crosslink (Pt-GG4).
(pdb code 4dl7). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Human Dna Polymerase Eta Fails to Extend Primer 2 Nucleotide After Cisplatin Crosslink (Pt-GG4)., PDB code: 4dl7: Platinum binding site 1 out of 1 in 4dl7Go back to![]() ![]()
Platinum binding site 1 out
of 1 in the Human Dna Polymerase Eta Fails to Extend Primer 2 Nucleotide After Cisplatin Crosslink (Pt-GG4).
![]() Mono view ![]() Stereo pair view
Reference:
Y.Zhao,
C.Biertumpfel,
M.T.Gregory,
Y.J.Hua,
F.Hanaoka,
W.Yang.
Structural Basis For Chemoresistance to Cisplatin Mediated By Dna Polymerase Eta Proc.Natl.Acad.Sci.Usa V. 109 7269 2012.
Page generated: Wed Dec 16 02:04:42 2020
ISSN: ISSN 0027-8424 PubMed: 22529383 DOI: 10.1073/PNAS.1202681109 |
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