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Platinum in PDB 4eey: Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct
Enzymatic activity of Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct
All present enzymatic activity of Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct, PDB code: 4eey
was solved by
A.Ummat,
O.Rechkoblit,
R.Jain,
J.R.Choudhury,
R.E.Johnson,
T.D.Silverstein,
A.Buku,
S.Lone,
L.Prakash,
S.Prakash,
A.K.Aggarwal,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 49.25 / 2.32 |
| Space group | P 61 |
| Cell size a, b, c (Å), α, β, γ (°) | 98.500, 98.500, 82.603, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 17.8 / 23.3 |
Other elements in 4eey:
The structure of Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct also contains other interesting chemical elements:
| Magnesium | (Mg) | 1 atom |
Platinum Binding Sites:
The binding sites of Platinum atom in the Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct
(pdb code 4eey). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct, PDB code: 4eey:
In total only one binding site of Platinum was determined in the Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct, PDB code: 4eey:
Platinum binding site 1 out of 1 in 4eey
Go back to
Platinum Binding Sites List in 4eey
Platinum binding site 1 out
of 1 in the Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Platinum with other atoms in the Pt binding
site number 1 of Crystal Structure of Human Dna Polymerase Eta in Ternary Complex with A Cisplatin Dna Adduct within 5.0Å range:
|
Reference:
A.Ummat,
O.Rechkoblit,
R.Jain,
J.Roy Choudhury,
R.E.Johnson,
T.D.Silverstein,
A.Buku,
S.Lone,
L.Prakash,
S.Prakash,
A.K.Aggarwal.
Structural Basis For Cisplatin Dna Damage Tolerance By Human Polymerase {Eta} During Cancer Chemotherapy. Nat.Struct.Mol.Biol. V. 19 628 2012.
ISSN: ISSN 1545-9993
PubMed: 22562137
DOI: 10.1038/NSMB.2295
Page generated: Wed Dec 16 02:04:44 2020
ISSN: ISSN 1545-9993
PubMed: 22562137
DOI: 10.1038/NSMB.2295
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