Atomistry » Platinum » PDB 4dd7-4nsj » 4lt0
Atomistry »
  Platinum »
    PDB 4dd7-4nsj »
      4lt0 »

Platinum in PDB 4lt0: Hewl Co-Crystallized with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Eval Software Package

Enzymatic activity of Hewl Co-Crystallized with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Eval Software Package

All present enzymatic activity of Hewl Co-Crystallized with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Eval Software Package:
3.2.1.17;

Protein crystallography data

The structure of Hewl Co-Crystallized with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Eval Software Package, PDB code: 4lt0 was solved by S.W.M.Tanley, K.Diederichs, L.M.J.Kroon-Batenburg, A.M.M.Schreurs, J.R.Helliwell, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.19 / 2.10
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 76.745, 76.745, 36.315, 90.00, 90.00, 90.00
R / Rfree (%) 22.3 / 28.3

Platinum Binding Sites:

The binding sites of Platinum atom in the Hewl Co-Crystallized with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Eval Software Package (pdb code 4lt0). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Hewl Co-Crystallized with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Eval Software Package, PDB code: 4lt0:

Platinum binding site 1 out of 1 in 4lt0

Go back to Platinum Binding Sites List in 4lt0
Platinum binding site 1 out of 1 in the Hewl Co-Crystallized with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Eval Software Package


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Hewl Co-Crystallized with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Eval Software Package within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt204

b:57.1
occ:0.39
 PT1 A:QPT204 0.0 57.1 0.4
O1 A:QPT204 2.0 57.4 1.0
O2 A:QPT204 2.0 65.1 1.0
ND1 A:HIS15 2.5 26.7 1.0
C1 A:QPT204 2.9 53.9 1.0
O4 A:QPT204 3.3 55.0 1.0
CE1 A:HIS15 3.4 26.7 1.0
CG A:HIS15 3.5 26.0 1.0
CB A:HIS15 3.7 25.4 1.0
CA A:HIS15 3.9 26.1 1.0
O A:HIS15 4.2 29.0 1.0
OD1 A:ASN93 4.3 32.9 1.0
CG2 A:THR89 4.5 25.5 1.0
NE2 A:HIS15 4.5 25.6 1.0
C A:HIS15 4.5 26.5 1.0
CD2 A:HIS15 4.6 25.6 1.0
OG1 A:THR89 4.9 24.6 1.0

Reference:

S.W.Tanley, K.Diederichs, L.M.Kroon-Batenburg, C.Levy, A.M.Schreurs, J.R.Helliwell. Carboplatin Binding to Histidine. Acta Crystallogr.,Sect.F V. 70 1135 2014.
ISSN: ISSN 1744-3091
PubMed: 25195881
DOI: 10.1107/S2053230X14016161
Page generated: Thu Oct 10 11:03:56 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy