Atomistry » Platinum » PDB 4dd7-4nsj » 4lt1
Atomistry »
  Platinum »
    PDB 4dd7-4nsj »
      4lt1 »

Platinum in PDB 4lt1: Hewl Co-Crystallised with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Xds Software Package

Enzymatic activity of Hewl Co-Crystallised with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Xds Software Package

All present enzymatic activity of Hewl Co-Crystallised with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Xds Software Package:
3.2.1.17;

Protein crystallography data

The structure of Hewl Co-Crystallised with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Xds Software Package, PDB code: 4lt1 was solved by S.W.M.Tanley, K.Diederichs, L.M.J.Kroon-Batenburg, A.M.M.Schreurs, J.R.Helliwell, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.38 / 2.30
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 76.820, 76.820, 36.470, 90.00, 90.00, 90.00
R / Rfree (%) 18.6 / 24.8

Platinum Binding Sites:

The binding sites of Platinum atom in the Hewl Co-Crystallised with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Xds Software Package (pdb code 4lt1). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Hewl Co-Crystallised with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Xds Software Package, PDB code: 4lt1:

Platinum binding site 1 out of 1 in 4lt1

Go back to Platinum Binding Sites List in 4lt1
Platinum binding site 1 out of 1 in the Hewl Co-Crystallised with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Xds Software Package


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Hewl Co-Crystallised with Carboplatin in Non-Nacl Conditions: Crystal 1 Processed Using the Xds Software Package within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt203

b:46.3
occ:0.29
 PT1 A:QPT203 0.0 46.3 0.3
O2 A:QPT203 2.0 49.8 1.0
O1 A:QPT203 2.0 51.4 1.0
ND1 A:HIS15 2.3 22.5 1.0
C1 A:QPT203 3.0 53.9 1.0
CE1 A:HIS15 3.2 23.0 1.0
CG A:HIS15 3.4 21.6 1.0
O4 A:QPT203 3.5 57.7 1.0
CA A:HIS15 3.7 23.3 1.0
CB A:HIS15 3.7 21.9 1.0
O A:HIS15 4.0 24.4 1.0
C A:HIS15 4.3 23.8 1.0
NE2 A:HIS15 4.4 22.8 1.0
CD2 A:HIS15 4.5 22.1 1.0
OD1 A:ASN93 4.7 34.2 1.0
CG2 A:THR89 4.7 20.0 1.0
N A:HIS15 4.9 23.8 1.0
OG1 A:THR89 4.9 19.8 1.0
O A:ARG14 5.0 25.5 1.0

Reference:

S.W.M.Tanley, K.Diederichs, L.M.J.Kroon-Batenburg, A.M.M.Schreurs, J.R.Helliwell. Carboplatin Binding to A Model Protein in Non-Nacl Conditions to Eliminate Partial Conversion to Cisplatin, and the Use of Different Criteria to Choose the Resolution Limit To Be Published.
Page generated: Thu Oct 10 11:04:27 2024

Last articles

Cl in 8CUR
Cl in 8CU9
Cl in 8CTY
Cl in 8CTM
Cl in 8CSD
Cl in 8CP8
Cl in 8CTB
Cl in 8CSC
Cl in 8CRM
Cl in 8CRH
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy