Platinum in PDB 4n10: Crystal Structure of Plasmodium Falciparum Oxidized Glutaredoxin 1 (PFGRX1) Complexed with Cisplatin

Enzymatic activity of Crystal Structure of Plasmodium Falciparum Oxidized Glutaredoxin 1 (PFGRX1) Complexed with Cisplatin

Protein crystallography data

Other elements in 4n10:

Platinum Binding Sites:

Platinum binding site 1 out of 3 in 4n10

Platinum Binding Sites List in 4n10

Platinum binding site 1 out of 3 in the Crystal Structure of Plasmodium Falciparum Oxidized Glutaredoxin 1 (PFGRX1) Complexed with Cisplatin


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Crystal Structure of Plasmodium Falciparum Oxidized Glutaredoxin 1 (PFGRX1) Complexed with Cisplatin within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt203 b:36.8 occ:0.40 PT1 A:CPT203 0.0 36.8 0.4 SD A:MET59 2.2 35.7 1.0 CL1 A:CPT203 2.3 38.3 0.4 CE A:MET59 2.9 47.8 1.0 OE1 A:GLN63 3.1 32.2 0.5 CG A:MET59 3.2 41.0 1.0 OE1 A:GLN63 3.2 31.8 0.5 CB A:MET59 4.1 30.9 1.0 O A:HOH354 4.2 45.4 1.0 CD A:GLN63 4.3 28.4 0.5 O A:HOH321 4.3 36.9 1.0 CD A:GLN63 4.4 28.6 0.5 NE2 A:GLN63 4.8 34.0 0.5

Platinum binding site 2 out of 3 in 4n10

Platinum Binding Sites List in 4n10

Platinum binding site 2 out of 3 in the Crystal Structure of Plasmodium Falciparum Oxidized Glutaredoxin 1 (PFGRX1) Complexed with Cisplatin


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 2 of Crystal Structure of Plasmodium Falciparum Oxidized Glutaredoxin 1 (PFGRX1) Complexed with Cisplatin within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt204 b:31.6 occ:0.54 PT1 A:CPT204 0.0 31.6 0.5 N1 A:CPT205 1.6 36.3 0.5 PT1 A:CPT205 1.8 38.4 0.5 ND1 A:HIS49 2.2 50.0 1.0 CL2 A:CPT204 2.3 44.6 0.5 CL1 A:CPT204 2.4 37.3 0.5 N1 A:CPT204 2.6 35.8 0.5 CG A:HIS49 3.0 41.1 1.0 CE1 A:HIS49 3.1 45.1 1.0 CB A:HIS49 3.4 34.9 1.0 CL2 A:CPT205 3.8 43.5 0.5 CL1 A:CPT205 3.9 40.4 0.5 OD1 A:ASN19 3.9 30.7 1.0 CD2 A:HIS49 4.0 50.5 1.0 NE2 A:HIS49 4.0 46.8 1.0 CA A:HIS49 4.2 30.0 1.0 O A:HOH336 4.5 42.1 1.0 CG A:ASN19 4.6 35.4 1.0 O A:MET48 4.6 29.4 0.5 O A:HOH345 4.7 37.5 0.8 ND2 A:ASN19 4.7 28.9 1.0 O A:HOH353 4.8 39.3 1.0 O A:MET48 4.8 29.4 0.5 O A:HOH347 4.9 36.2 0.9

Platinum binding site 3 out of 3 in 4n10

Platinum Binding Sites List in 4n10

Platinum binding site 3 out of 3 in the Crystal Structure of Plasmodium Falciparum Oxidized Glutaredoxin 1 (PFGRX1) Complexed with Cisplatin


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 3 of Crystal Structure of Plasmodium Falciparum Oxidized Glutaredoxin 1 (PFGRX1) Complexed with Cisplatin within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt205 b:38.4 occ:0.46 PT1 A:CPT205 0.0 38.4 0.5 CL2 A:CPT204 0.5 44.6 0.5 PT1 A:CPT204 1.8 31.6 0.5 CL1 A:CPT205 2.3 40.4 0.5 N1 A:CPT205 2.3 36.3 0.5 ND1 A:HIS49 2.5 50.0 1.0 CL2 A:CPT205 2.5 43.5 0.5 CL1 A:CPT204 3.3 37.3 0.5 CG A:HIS49 3.3 41.1 1.0 CB A:HIS49 3.4 34.9 1.0 CE1 A:HIS49 3.5 45.1 1.0 CA A:HIS49 3.5 30.0 1.0 O A:MET48 3.5 29.4 0.5 O A:MET48 3.6 29.4 0.5 O A:HOH347 3.8 36.2 0.9 C A:MET48 4.4 29.2 0.5 N1 A:CPT204 4.4 35.8 0.5 C A:MET48 4.4 29.2 0.5 N A:HIS49 4.4 25.7 1.0 O A:HOH345 4.5 37.5 0.8 CD2 A:HIS49 4.5 50.5 1.0 N A:VAL50 4.6 24.8 1.0 C A:HIS49 4.6 26.8 1.0 NE2 A:HIS49 4.6 46.8 1.0 OD1 A:ASN19 4.9 30.7 1.0

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