Platinum in PDB 4owh: PTBR6 Binding to Hewl

All present enzymatic activity of PTBR6 Binding to Hewl:
3.2.1.17;

The structure of PTBR6 Binding to Hewl, PDB code: 4owh was solved by S.W.M.Tanley, V.L.Starkey, L.Lamplough, S.Kaenket, J.R.Helliwell, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	55.62 / 1.48
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	78.663, 78.663, 36.845, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 22.3

The structure of PTBR6 Binding to Hewl also contains other interesting chemical elements:

Bromine	(Br)	12 atoms
Chlorine	(Cl)	9 atoms
Sodium	(Na)	1 atom

The binding sites of Platinum atom in the PTBR6 Binding to Hewl (pdb code 4owh). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total 2 binding sites of Platinum where determined in the PTBR6 Binding to Hewl, PDB code: 4owh:
Jump to Platinum binding site number: 1; 2;

Platinum binding site 1 out of 2 in the PTBR6 Binding to Hewl


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of PTBR6 Binding to Hewl within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt201 b:19.7 occ:0.47 PT A:6BP201 0.0 19.7 0.5 BR4 A:6BP201 2.4 26.1 0.5 BR1 A:6BP201 2.4 18.5 0.5 BR3 A:6BP201 2.5 22.6 0.5 BR2 A:6BP201 2.5 25.5 0.5 O A:HOH379 4.4 25.6 1.0 NE A:ARG14 4.4 26.4 1.0

Platinum binding site 2 out of 2 in the PTBR6 Binding to Hewl


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 2 of PTBR6 Binding to Hewl within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt202 b:17.4 occ:0.52 PT A:6BP202 0.0 17.4 0.5 BR4 A:6BP202 2.3 19.3 0.5 BR5 A:6BP202 2.4 24.0 0.5 BR3 A:6BP202 2.4 24.8 0.5 BR6 A:6BP202 2.4 20.7 0.5 BR1 A:6BP202 2.5 24.7 0.5 BR2 A:6BP202 2.5 18.5 0.5 O A:HOH320 4.2 19.5 1.0 O A:HOH338 4.6 23.5 1.0

S.W.Tanley, L.V.Starkey, L.Lamplough, S.Kaenket, J.R.Helliwell. The Binding of Platinum Hexahalides (Cl, Br and I) to Hen Egg-White Lysozyme and the Chemical Transformation of the PTI6 Octahedral Complex to A PTI3 Moiety Bound to HIS15. Acta Crystallogr.,Sect.F V. 70 1132 2014.
ISSN: ESSN 2053-230X
PubMed: 25195880
DOI: 10.1107/S2053230X14014009