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Atomistry » Platinum » PDB 4omb-5djl » 4q8e | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Platinum » PDB 4omb-5djl » 4q8e » |
Platinum in PDB 4q8e: Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted GEnzymatic activity of Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted G
All present enzymatic activity of Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted G:
2.7.7.7; Protein crystallography data
The structure of Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted G, PDB code: 4q8e
was solved by
M.T.Gregory,
W.Yang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4q8e:
The structure of Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted G also contains other interesting chemical elements:
Platinum Binding Sites:
The binding sites of Platinum atom in the Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted G
(pdb code 4q8e). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total 2 binding sites of Platinum where determined in the Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted G, PDB code: 4q8e: Jump to Platinum binding site number: 1; 2; Platinum binding site 1 out of 2 in 4q8eGo back to Platinum Binding Sites List in 4q8e
Platinum binding site 1 out
of 2 in the Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted G
Mono view Stereo pair view
Platinum binding site 2 out of 2 in 4q8eGo back to Platinum Binding Sites List in 4q8e
Platinum binding site 2 out
of 2 in the Human Dna Polymerase Eta Inserting Dcmpnpp Opposite A Phenanthriplatin Adducted G
Mono view Stereo pair view
Reference:
M.T.Gregory,
G.Y.Park,
T.C.Johnstone,
Y.S.Lee,
W.Yang,
S.J.Lippard.
Structural and Mechanistic Studies of Polymerase Eta Bypass of Phenanthriplatin Dna Damage. Proc.Natl.Acad.Sci.Usa V. 111 9133 2014.
Page generated: Thu Oct 10 11:08:42 2024
ISSN: ISSN 0027-8424 PubMed: 24927576 DOI: 10.1073/PNAS.1405739111 |
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