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Atomistry » Platinum » PDB 4nsj-5bna » 4tur | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Platinum » PDB 4nsj-5bna » 4tur » |
Platinum in PDB 4tur: Human Dna Polymerase Beta Inserting Dcmpnpp Opposite the 5'G of Cisplatin Crosslinked Gs (Pt-GG2)Enzymatic activity of Human Dna Polymerase Beta Inserting Dcmpnpp Opposite the 5'G of Cisplatin Crosslinked Gs (Pt-GG2)
All present enzymatic activity of Human Dna Polymerase Beta Inserting Dcmpnpp Opposite the 5'G of Cisplatin Crosslinked Gs (Pt-GG2):
2.7.7.7; Protein crystallography data
The structure of Human Dna Polymerase Beta Inserting Dcmpnpp Opposite the 5'G of Cisplatin Crosslinked Gs (Pt-GG2), PDB code: 4tur
was solved by
M.C.Koag,
S.Lee,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4tur:
The structure of Human Dna Polymerase Beta Inserting Dcmpnpp Opposite the 5'G of Cisplatin Crosslinked Gs (Pt-GG2) also contains other interesting chemical elements:
Platinum Binding Sites:
The binding sites of Platinum atom in the Human Dna Polymerase Beta Inserting Dcmpnpp Opposite the 5'G of Cisplatin Crosslinked Gs (Pt-GG2)
(pdb code 4tur). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Human Dna Polymerase Beta Inserting Dcmpnpp Opposite the 5'G of Cisplatin Crosslinked Gs (Pt-GG2), PDB code: 4tur: Platinum binding site 1 out of 1 in 4turGo back to![]() ![]()
Platinum binding site 1 out
of 1 in the Human Dna Polymerase Beta Inserting Dcmpnpp Opposite the 5'G of Cisplatin Crosslinked Gs (Pt-GG2)
![]() Mono view ![]() Stereo pair view
Reference:
M.C.Koag,
L.Lai,
S.Lee.
Structural Basis For the Inefficient Nucleotide Incorporation Opposite Cisplatin-Dna Lesion By Human Dna Polymerase Beta J.Biol.Chem. 2014.
Page generated: Wed Dec 16 02:05:04 2020
ISSN: ESSN 1083-351X PubMed: 25237188 DOI: 10.1074/JBC.M114.605451 |
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