Atomistry » Platinum » PDB 4nsj-5bna » 4ydx
Atomistry »
  Platinum »
    PDB 4nsj-5bna »
      4ydx »

Platinum in PDB 4ydx: Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement

Protein crystallography data

The structure of Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement, PDB code: 4ydx was solved by I.G.Shabalin, A.K.Boal, Z.Dauter, M.Jaskolski, W.Minor, A.C.Rosenzweig, A.Wlodawer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.03 / 1.60
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 54.070, 54.070, 55.578, 90.00, 90.00, 120.00
R / Rfree (%) 13.6 / 15.6

Platinum Binding Sites:

The binding sites of Platinum atom in the Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement (pdb code 4ydx). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement, PDB code: 4ydx:

Platinum binding site 1 out of 1 in 4ydx

Go back to Platinum Binding Sites List in 4ydx
Platinum binding site 1 out of 1 in the Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt101

b:19.8
occ:0.90
N A:CYS12 2.1 20.4 1.0
SG A:CYS12 2.3 24.7 1.0
P A:TCE103 2.3 22.8 0.9
SG A:CYS15 2.3 19.7 1.0
CA A:CYS12 2.9 21.5 1.0
C A:THR11 3.2 21.4 1.0
CB A:CYS12 3.2 23.7 1.0
C2 A:TCE103 3.3 33.3 0.9
C A:CYS12 3.4 21.0 1.0
CB A:CYS15 3.4 17.4 1.0
CB A:THR11 3.5 23.3 1.0
C3 A:TCE103 3.5 38.6 0.9
O A:CYS12 3.5 19.1 1.0
CA A:THR11 3.6 21.4 1.0
C1 A:TCE103 3.6 30.6 0.9
N A:CYS15 3.7 16.9 1.0
N A:THR11 3.8 19.5 1.0
C5 A:TCE103 3.9 33.8 0.9
CG2 A:THR11 4.0 25.5 1.0
C4 A:TCE103 4.1 29.2 0.9
CA A:CYS15 4.1 16.4 1.0
O A:THR11 4.2 22.9 1.0
N A:GLY13 4.3 21.0 1.0
O A:HOH225 4.4 33.1 1.0
N A:GLY14 4.5 19.4 1.0
C A:GLY14 4.6 17.4 1.0
OG1 A:THR11 4.7 24.4 1.0
CA A:GLY14 4.8 18.9 1.0
C6 A:TCE103 4.9 41.3 0.9
O A:HOH206 4.9 28.7 1.0

Reference:

I.G.Shabalin, Z.Dauter, M.Jaskolski, W.Minor, A.Wlodawer. Crystallography and Chemistry Should Always Go Together: A Cautionary Tale of Protein Complexes with Cisplatin and Carboplatin To Be Published.
Page generated: Wed Dec 16 02:05:04 2020

Last articles

Zn in 7L0B
Zn in 7KZZ
Zn in 7KZL
Zn in 7L3O
Zn in 7L52
Zn in 7L6T
Zn in 7KZ7
Zn in 7L6R
Zn in 7KKM
Zn in 7KKQ
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy