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Atomistry » Platinum » PDB 4nsj-5bna » 4z46 » |
Platinum in PDB 4z46: X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and OxaliplatinEnzymatic activity of X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and Oxaliplatin
All present enzymatic activity of X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and Oxaliplatin:
3.2.1.17; Protein crystallography data
The structure of X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and Oxaliplatin, PDB code: 4z46
was solved by
A.Merlino,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4z46:
The structure of X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and Oxaliplatin also contains other interesting chemical elements:
Platinum Binding Sites:
The binding sites of Platinum atom in the X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and Oxaliplatin
(pdb code 4z46). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total 2 binding sites of Platinum where determined in the X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and Oxaliplatin, PDB code: 4z46: Jump to Platinum binding site number: 1; 2; Platinum binding site 1 out of 2 in 4z46Go back to![]() ![]()
Platinum binding site 1 out
of 2 in the X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and Oxaliplatin
![]() Mono view ![]() Stereo pair view
Platinum binding site 2 out of 2 in 4z46Go back to![]() ![]()
Platinum binding site 2 out
of 2 in the X-Ray Structure of the Bis-Platinum Lysozyme Adduct Formed in the Reaction Between the Protein and the Two Drugs Cisplatin and Oxaliplatin
![]() Mono view ![]() Stereo pair view
Reference:
D.Marasco,
L.Messori,
T.Marzo,
A.Merlino.
Oxaliplatin Vs. Cisplatin: Competition Experiments on Their Binding to Lysozyme. Dalton Trans 2015.
Page generated: Wed Dec 16 02:05:07 2020
ISSN: ESSN 1477-9234 PubMed: 25974859 DOI: 10.1039/C5DT01279A |
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