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Atomistry » Platinum » PDB 5djl-5t7l » 5t7l » |
Platinum in PDB 5t7l: Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1Enzymatic activity of Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1
All present enzymatic activity of Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1:
3.6.3.54; Protein crystallography data
The structure of Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1, PDB code: 5t7l
was solved by
R.Caliandro,
V.Mirabelli,
R.Caliandro,
A.Rosato,
A.Lasorsa,
A.Galliani,
F.Arnesano,
G.Natile,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5t7l:
The structure of Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1 also contains other interesting chemical elements:
Platinum Binding Sites:
The binding sites of Platinum atom in the Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1
(pdb code 5t7l). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total 2 binding sites of Platinum where determined in the Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1, PDB code: 5t7l: Jump to Platinum binding site number: 1; 2; Platinum binding site 1 out of 2 in 5t7lGo back to![]() ![]()
Platinum binding site 1 out
of 2 in the Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1
![]() Mono view ![]() Stereo pair view
Platinum binding site 2 out of 2 in 5t7lGo back to![]() ![]()
Platinum binding site 2 out
of 2 in the Pt(II)-Mediated Copper-Dependent Interactions Between ATOX1 and MNK1
![]() Mono view ![]() Stereo pair view
Reference:
A.Lasorsa,
M.I.Nardella,
A.Rosato,
V.Mirabelli,
R.Caliandro,
R.Caliandro,
G.Natile,
F.Arnesano.
Mechanistic and Structural Basis For Inhibition of Copper Trafficking By Platinum Anticancer Drugs. J.Am.Chem.Soc. V. 141 12109 2019.
Page generated: Wed Dec 16 02:05:24 2020
ISSN: ESSN 1520-5126 PubMed: 31283225 DOI: 10.1021/JACS.9B05550 |
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