Platinum in PDB 5z80: Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex
Platinum Binding Sites:
The binding sites of Platinum atom in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex
(pdb code 5z80). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total 3 binding sites of Platinum where determined in the
Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex, PDB code: 5z80:
Jump to Platinum binding site number:
1;
2;
3;
Platinum binding site 1 out
of 3 in 5z80
Go back to
Platinum Binding Sites List in 5z80
Platinum binding site 1 out
of 3 in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex
Mono view
Stereo pair view
|
A full contact list of Platinum with other atoms in the Pt binding
site number 1 of Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Pt101
b:0.3
occ:1.00
|
PT2
|
A:9F0101
|
0.0
|
0.3
|
1.0
|
N49
|
A:9F0101
|
2.0
|
0.4
|
1.0
|
N35
|
A:9F0101
|
2.0
|
0.3
|
1.0
|
N41
|
A:9F0101
|
2.0
|
0.4
|
1.0
|
N42
|
A:9F0101
|
2.1
|
0.6
|
1.0
|
H49
|
A:9F0101
|
2.5
|
0.4
|
1.0
|
H41
|
A:9F0101
|
2.6
|
0.4
|
1.0
|
H9Y
|
A:9F0101
|
2.6
|
0.6
|
1.0
|
H9X
|
A:9F0101
|
2.6
|
0.5
|
1.0
|
H42
|
A:9F0101
|
2.6
|
0.7
|
1.0
|
C51
|
A:9F0101
|
2.8
|
0.4
|
1.0
|
C52
|
A:9F0101
|
2.8
|
0.6
|
1.0
|
C50
|
A:9F0101
|
2.9
|
0.4
|
1.0
|
C53
|
A:9F0101
|
2.9
|
0.7
|
1.0
|
C36
|
A:9F0101
|
3.0
|
0.3
|
1.0
|
C34
|
A:9F0101
|
3.0
|
0.3
|
1.0
|
H51
|
A:9F0101
|
3.0
|
0.5
|
1.0
|
H52
|
A:9F0101
|
3.0
|
0.7
|
1.0
|
H36
|
A:9F0101
|
3.0
|
0.3
|
1.0
|
H34
|
A:9F0101
|
3.0
|
0.4
|
1.0
|
H9L
|
A:9F0101
|
3.4
|
0.4
|
1.0
|
H9O
|
A:9F0101
|
3.4
|
0.7
|
1.0
|
H53
|
A:9F0101
|
3.8
|
0.8
|
1.0
|
H50
|
A:9F0101
|
3.8
|
0.5
|
1.0
|
H9N
|
A:9F0101
|
3.8
|
0.6
|
1.0
|
H9M
|
A:9F0101
|
3.8
|
0.5
|
1.0
|
C37
|
A:9F0101
|
4.3
|
0.3
|
1.0
|
C33
|
A:9F0101
|
4.3
|
0.3
|
1.0
|
C21
|
A:9F0101
|
4.8
|
0.2
|
1.0
|
|
Platinum binding site 2 out
of 3 in 5z80
Go back to
Platinum Binding Sites List in 5z80
Platinum binding site 2 out
of 3 in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex
Mono view
Stereo pair view
|
A full contact list of Platinum with other atoms in the Pt binding
site number 2 of Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Pt101
b:0.4
occ:1.00
|
PT1
|
A:9F0101
|
0.0
|
0.4
|
1.0
|
N46
|
A:9F0101
|
2.0
|
0.5
|
1.0
|
N30
|
A:9F0101
|
2.0
|
0.4
|
1.0
|
N47
|
A:9F0101
|
2.0
|
0.5
|
1.0
|
N48
|
A:9F0101
|
2.1
|
0.5
|
1.0
|
H46
|
A:9F0101
|
2.5
|
0.5
|
1.0
|
H47
|
A:9F0101
|
2.6
|
0.6
|
1.0
|
H91
|
A:9F0101
|
2.6
|
0.6
|
1.0
|
H92
|
A:9F0101
|
2.6
|
0.5
|
1.0
|
H48
|
A:9F0101
|
2.6
|
0.5
|
1.0
|
C61
|
A:9F0101
|
2.8
|
0.6
|
1.0
|
C59
|
A:9F0101
|
2.8
|
0.5
|
1.0
|
C60
|
A:9F0101
|
2.9
|
0.6
|
1.0
|
C58
|
A:9F0101
|
2.9
|
0.6
|
1.0
|
C29
|
A:9F0101
|
3.0
|
0.4
|
1.0
|
C31
|
A:9F0101
|
3.0
|
0.3
|
1.0
|
H29
|
A:9F0101
|
3.0
|
0.5
|
1.0
|
H61
|
A:9F0101
|
3.0
|
0.6
|
1.0
|
H59
|
A:9F0101
|
3.0
|
0.6
|
1.0
|
H31
|
A:9F0101
|
3.1
|
0.4
|
1.0
|
H9V
|
A:9F0101
|
3.4
|
0.6
|
1.0
|
H9T
|
A:9F0101
|
3.4
|
0.6
|
1.0
|
H58
|
A:9F0101
|
3.8
|
0.6
|
1.0
|
H60
|
A:9F0101
|
3.8
|
0.7
|
1.0
|
H9U
|
A:9F0101
|
3.8
|
0.6
|
1.0
|
H9W
|
A:9F0101
|
3.8
|
0.6
|
1.0
|
O2
|
A:DT19
|
4.2
|
0.6
|
1.0
|
C28
|
A:9F0101
|
4.3
|
0.4
|
1.0
|
C32
|
A:9F0101
|
4.3
|
0.3
|
1.0
|
H3
|
A:DT19
|
4.4
|
0.7
|
1.0
|
C22
|
A:9F0101
|
4.8
|
0.3
|
1.0
|
|
Platinum binding site 3 out
of 3 in 5z80
Go back to
Platinum Binding Sites List in 5z80
Platinum binding site 3 out
of 3 in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex
Mono view
Stereo pair view
|
A full contact list of Platinum with other atoms in the Pt binding
site number 3 of Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Pt101
b:0.4
occ:1.00
|
PT3
|
A:9F0101
|
0.0
|
0.4
|
1.0
|
N45
|
A:9F0101
|
2.0
|
0.4
|
1.0
|
N44
|
A:9F0101
|
2.0
|
0.5
|
1.0
|
N43
|
A:9F0101
|
2.1
|
0.5
|
1.0
|
N25
|
A:9F0101
|
2.1
|
0.3
|
1.0
|
H45
|
A:9F0101
|
2.5
|
0.5
|
1.0
|
H90
|
A:9F0101
|
2.6
|
0.5
|
1.0
|
H44
|
A:9F0101
|
2.6
|
0.5
|
1.0
|
H43
|
A:9F0101
|
2.6
|
0.5
|
1.0
|
H9Z
|
A:9F0101
|
2.6
|
0.5
|
1.0
|
C56
|
A:9F0101
|
2.8
|
0.5
|
1.0
|
C55
|
A:9F0101
|
2.8
|
0.5
|
1.0
|
C54
|
A:9F0101
|
2.8
|
0.5
|
1.0
|
C57
|
A:9F0101
|
2.9
|
0.6
|
1.0
|
C24
|
A:9F0101
|
3.0
|
0.3
|
1.0
|
C26
|
A:9F0101
|
3.0
|
0.3
|
1.0
|
H55
|
A:9F0101
|
3.0
|
0.5
|
1.0
|
H56
|
A:9F0101
|
3.0
|
0.5
|
1.0
|
H24
|
A:9F0101
|
3.0
|
0.4
|
1.0
|
H26
|
A:9F0101
|
3.0
|
0.4
|
1.0
|
H9P
|
A:9F0101
|
3.2
|
0.6
|
1.0
|
H9S
|
A:9F0101
|
3.4
|
0.6
|
1.0
|
H57
|
A:9F0101
|
3.8
|
0.7
|
1.0
|
H9R
|
A:9F0101
|
3.8
|
0.5
|
1.0
|
H54
|
A:9F0101
|
3.8
|
0.6
|
1.0
|
H9Q
|
A:9F0101
|
3.8
|
0.5
|
1.0
|
C23
|
A:9F0101
|
4.3
|
0.3
|
1.0
|
C27
|
A:9F0101
|
4.3
|
0.3
|
1.0
|
C20
|
A:9F0101
|
4.8
|
0.3
|
1.0
|
O4
|
A:DT8
|
4.9
|
0.8
|
1.0
|
|
Reference:
W.Liu,
Y.F.Zhong,
L.Y.Liu,
C.T.Shen,
W.Zeng,
F.Wang,
D.Yang,
Z.W.Mao.
Solution Structures of Multiple G-Quadruplex Complexes Induced By A Platinum(II)-Based Tripod Reveal Dynamic Binding Nat Commun V. 9 3496 2018.
ISSN: ESSN 2041-1723
PubMed: 30158518
DOI: 10.1038/S41467-018-05810-4
Page generated: Thu Oct 10 11:41:56 2024
|