Atomistry » Platinum » PDB 5v6i-7kem » 6hjt
Atomistry »
  Platinum »
    PDB 5v6i-7kem »
      6hjt »

Platinum in PDB 6hjt: The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage

Protein crystallography data

The structure of The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage, PDB code: 6hjt was solved by A.Pica, G.Ferraro, A.Merlino, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.30 / 1.33
Space group F 4 3 2
Cell size a, b, c (Å), α, β, γ (°) 181.156, 181.156, 181.156, 90.00, 90.00, 90.00
R / Rfree (%) 12.7 / 15.7

Other elements in 6hjt:

The structure of The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage also contains other interesting chemical elements:

Cadmium (Cd) 7 atoms
Chlorine (Cl) 4 atoms

Platinum Binding Sites:

The binding sites of Platinum atom in the The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage (pdb code 6hjt). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total 5 binding sites of Platinum where determined in the The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage, PDB code: 6hjt:
Jump to Platinum binding site number: 1; 2; 3; 4; 5;

Platinum binding site 1 out of 5 in 6hjt

Go back to Platinum Binding Sites List in 6hjt
Platinum binding site 1 out of 5 in the The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt210

b:48.8
occ:0.30
O A:HOH304 2.0 50.7 0.3
O A:HOH474 2.1 46.2 0.3
NE2 A:HIS49 2.1 42.2 1.0
O A:HOH527 2.1 54.7 0.3
CD2 A:HIS49 2.9 41.8 1.0
CE1 A:HIS49 3.3 30.4 1.0
O A:HOH525 4.0 79.4 1.0
CG A:HIS49 4.1 39.0 1.0
CG A:GLU53 4.2 19.9 0.5
ND1 A:HIS49 4.3 58.7 1.0
CD A:GLU53 4.6 27.6 0.5
OE1 A:GLU53 4.9 53.2 0.5

Platinum binding site 2 out of 5 in 6hjt

Go back to Platinum Binding Sites List in 6hjt
Platinum binding site 2 out of 5 in the The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 2 of The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt211

b:34.9
occ:0.35
O A:HOH378 1.7 27.5 0.3
O A:HOH311 1.9 22.4 0.3
O A:HOH519 2.0 40.4 0.3
ND1 A:HIS132 2.0 38.7 1.0
CE1 A:HIS132 3.0 53.3 1.0
CG A:HIS132 3.1 32.6 1.0
CB A:HIS132 3.4 31.2 1.0
CA A:HIS132 3.6 23.1 1.0
O A:SER131 4.0 34.8 1.0
NE2 A:HIS132 4.1 60.7 1.0
CD2 A:HIS132 4.2 40.1 1.0
NE A:ARG64 4.2 45.4 0.5
O A:HIS132 4.5 25.6 1.0
CZ A:ARG64 4.5 56.9 0.5
N A:HIS132 4.5 23.5 1.0
C A:SER131 4.6 28.3 1.0
C A:HIS132 4.6 22.7 1.0
NH2 A:ARG64 4.7 75.5 0.5
CD A:ARG64 4.7 31.2 0.5
NE A:ARG64 4.8 48.7 0.6
CD A:ARG64 4.8 29.6 0.6

Platinum binding site 3 out of 5 in 6hjt

Go back to Platinum Binding Sites List in 6hjt
Platinum binding site 3 out of 5 in the The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 3 of The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt212

b:59.2
occ:0.40
O A:HOH422 1.9 42.4 0.4
ND1 A:HIS49 2.0 58.7 1.0
O A:HOH334 2.5 56.3 0.4
CL A:CL218 2.7 67.1 0.4
CE1 A:HIS49 2.9 30.4 1.0
CG A:HIS49 3.0 39.0 1.0
CB A:HIS49 3.3 18.9 1.0
NE2 A:HIS49 4.0 42.2 1.0
CD2 A:HIS49 4.0 41.8 1.0
CA A:HIS49 4.1 14.8 1.0
CD A:CD205 4.3 35.9 0.3
O A:HOH524 4.5 51.0 1.0
CL A:CL218 4.6 41.5 0.3
N A:HIS49 4.9 14.0 1.0
OE2 A:GLU45 5.0 49.5 0.5

Platinum binding site 4 out of 5 in 6hjt

Go back to Platinum Binding Sites List in 6hjt
Platinum binding site 4 out of 5 in the The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 4 of The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt213

b:61.8
occ:0.25
NE2 A:HIS132 2.0 60.7 1.0
O A:HOH438 2.0 36.7 0.2
C1 A:DMS217 2.0 32.9 0.2
S A:DMS217 2.2 20.5 0.2
CE1 A:HIS132 2.6 53.3 1.0
C2 A:DMS217 3.0 30.1 0.2
CD2 A:HIS132 3.3 40.1 1.0
O A:DMS217 3.6 35.4 0.2
ND1 A:HIS132 3.8 38.7 1.0
O A:HOH497 4.1 45.5 1.0
CG A:HIS132 4.2 32.6 1.0
CB A:SER131 4.7 33.8 1.0

Platinum binding site 5 out of 5 in 6hjt

Go back to Platinum Binding Sites List in 6hjt
Platinum binding site 5 out of 5 in the The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 5 of The X-Ray Structure of the Horse Spleen Ferritin Nanocage Containing Pt, Obtained Upon Encapsulation of A Pt(II) Terpyridine Compound Within the Protein Cage within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Pt214

b:37.5
occ:0.20
NE2 A:HIS114 2.1 19.4 0.3
CE1 A:HIS114 2.3 28.1 0.7
CE1 A:HIS114 2.6 15.2 0.3
NE2 A:HIS114 2.7 29.9 0.7
O A:HOH363 2.9 29.1 0.4
OE2 A:GLU130 3.2 34.0 1.0
CB A:CYS126 3.3 25.2 1.0
SG A:CYS126 3.4 32.3 1.0
CD2 A:HIS114 3.4 19.5 0.3
ND1 A:HIS114 3.5 29.3 0.7
ND1 A:HIS114 3.8 19.6 0.3
CD2 A:HIS114 3.9 24.3 0.7
CG A:HIS114 4.2 18.4 0.3
CG A:HIS114 4.3 23.9 0.7
CD A:GLU130 4.5 40.6 1.0
CA A:CYS126 4.5 23.1 1.0
O A:HOH550 4.6 72.1 1.0
O A:HOH363 4.7 21.1 0.6
CB A:SER118 4.9 28.0 1.0

Reference:

G.Ferraro, A.Pica, G.Petruk, F.Pane, A.Amoresano, A.Cilibrizzi, R.Vilar, D.M.Monti, A.Merlino. Preparation, Structure, Cytotoxicity and Mechanism of Action of Ferritin-Pt(II) Terpyridine Compound Nanocomposites. Nanomedicine (Lond) V. 13 2995 2018.
ISSN: ISSN 1748-6963
PubMed: 30501559
DOI: 10.2217/NNM-2018-0259
Page generated: Wed Dec 16 02:05:36 2020

Last articles

Zn in 7M6U
Zn in 7NNG
Zn in 7NEE
Zn in 7NEU
Zn in 7M3K
Zn in 7KWD
Zn in 7KYH
Zn in 7KNG
Zn in 7KY2
Zn in 7KYF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy