Platinum in PDB 4ydx: Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement

The structure of Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement, PDB code: 4ydx was solved by I.G.Shabalin, A.K.Boal, Z.Dauter, M.Jaskolski, W.Minor, A.C.Rosenzweig, A.Wlodawer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.03 / 1.60
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	54.070, 54.070, 55.578, 90.00, 90.00, 120.00
R / Rfree (%)	13.6 / 15.6

The binding sites of Platinum atom in the Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement (pdb code 4ydx). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total only one binding site of Platinum was determined in the Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement, PDB code: 4ydx:

Platinum binding site 1 out of 1 in the Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Crystal Structure of Cisplatin Bound to A Human Copper Chaperone (Monomer) - New Refinement within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt101 b:19.8 occ:0.90 N A:CYS12 2.1 20.4 1.0 SG A:CYS12 2.3 24.7 1.0 P A:TCE103 2.3 22.8 0.9 SG A:CYS15 2.3 19.7 1.0 CA A:CYS12 2.9 21.5 1.0 C A:THR11 3.2 21.4 1.0 CB A:CYS12 3.2 23.7 1.0 C2 A:TCE103 3.3 33.3 0.9 C A:CYS12 3.4 21.0 1.0 CB A:CYS15 3.4 17.4 1.0 CB A:THR11 3.5 23.3 1.0 C3 A:TCE103 3.5 38.6 0.9 O A:CYS12 3.5 19.1 1.0 CA A:THR11 3.6 21.4 1.0 C1 A:TCE103 3.6 30.6 0.9 N A:CYS15 3.7 16.9 1.0 N A:THR11 3.8 19.5 1.0 C5 A:TCE103 3.9 33.8 0.9 CG2 A:THR11 4.0 25.5 1.0 C4 A:TCE103 4.1 29.2 0.9 CA A:CYS15 4.1 16.4 1.0 O A:THR11 4.2 22.9 1.0 N A:GLY13 4.3 21.0 1.0 O A:HOH225 4.4 33.1 1.0 N A:GLY14 4.5 19.4 1.0 C A:GLY14 4.6 17.4 1.0 OG1 A:THR11 4.7 24.4 1.0 CA A:GLY14 4.8 18.9 1.0 C6 A:TCE103 4.9 41.3 0.9 O A:HOH206 4.9 28.7 1.0

I.G.Shabalin, Z.Dauter, M.Jaskolski, W.Minor, A.Wlodawer. Crystallography and Chemistry Should Always Go Together: A Cautionary Tale of Protein Complexes with Cisplatin and Carboplatin To Be Published.