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Platinum in PDB 4yem: Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement
Enzymatic activity of Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement
All present enzymatic activity of Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement:
3.2.1.17;
3.2.1.17;
Protein crystallography data
The structure of Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement, PDB code: 4yem
was solved by
I.G.Shabalin,
Z.Dauter,
M.Jaskolski,
W.Minor,
A.Wlodawer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 39.29 / 1.47 |
| Space group | P 43 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 78.580, 78.580, 37.290, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 10.5 / 15.6 |
Other elements in 4yem:
The structure of Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement also contains other interesting chemical elements:
| Bromine | (Br) | 19 atoms |
| Chlorine | (Cl) | 1 atom |
| Sodium | (Na) | 1 atom |
Platinum Binding Sites:
The binding sites of Platinum atom in the Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement
(pdb code 4yem). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total 3 binding sites of Platinum where determined in the Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement, PDB code: 4yem:
Jump to Platinum binding site number: 1; 2; 3;
In total 3 binding sites of Platinum where determined in the Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement, PDB code: 4yem:
Jump to Platinum binding site number: 1; 2; 3;
Platinum binding site 1 out of 3 in 4yem
Go back to
Platinum Binding Sites List in 4yem
Platinum binding site 1 out
of 3 in the Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Platinum with other atoms in the Pt binding
site number 1 of Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement within 5.0Å range:
|
Platinum binding site 2 out of 3 in 4yem
Go back to
Platinum Binding Sites List in 4yem
Platinum binding site 2 out
of 3 in the Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Platinum with other atoms in the Pt binding
site number 2 of Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement within 5.0Å range:
|
Platinum binding site 3 out of 3 in 4yem
Go back to
Platinum Binding Sites List in 4yem
Platinum binding site 3 out
of 3 in the Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Platinum with other atoms in the Pt binding
site number 3 of Carboplatin Binding to Hewl in Nabr Crystallisation Conditions Studied at An X-Ray Wavelength of 0.9163A - New Refinement within 5.0Å range:
|
Reference:
I.G.Shabalin,
Z.Dauter,
M.Jaskolski,
W.Minor,
A.Wlodawer.
Crystallography and Chemistry Should Always Go Together: A Cautionary Tale of Protein Complexes with Cisplatin and Carboplatin To Be Published.
Page generated: Thu Oct 10 11:31:06 2024
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