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Atomistry » Platinum » PDB 5djm-5v6i » 5djm » |
Platinum in PDB 5djm: Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione.Enzymatic activity of Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione.
All present enzymatic activity of Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione.:
2.5.1.18; Protein crystallography data
The structure of Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione., PDB code: 5djm
was solved by
L.J.Parker,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Platinum Binding Sites:
The binding sites of Platinum atom in the Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione.
(pdb code 5djm). This binding sites where shown within
5.0 Angstroms radius around Platinum atom.
In total 3 binding sites of Platinum where determined in the Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione., PDB code: 5djm: Jump to Platinum binding site number: 1; 2; 3; Platinum binding site 1 out of 3 in 5djmGo back to![]() ![]()
Platinum binding site 1 out
of 3 in the Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione.
![]() Mono view ![]() Stereo pair view
Platinum binding site 2 out of 3 in 5djmGo back to![]() ![]()
Platinum binding site 2 out
of 3 in the Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione.
![]() Mono view ![]() Stereo pair view
Platinum binding site 3 out of 3 in 5djmGo back to![]() ![]()
Platinum binding site 3 out
of 3 in the Structure of Wt Human Glutathione Transferase in Complex with Cisplatin in the Absence of Glutathione.
![]() Mono view ![]() Stereo pair view
Reference:
L.J.Parker,
L.C.Italiano,
N.C.Hancock,
J.Aitken,
H.H.Harris,
G.Hansen,
D.B.Ascher,
C.J.Morton,
M.W.Parker,
M.Lo Bello.
A Structure-Based Mechanism of Cisplatin Resistance Mediated By Glutathione Transferase P1-1 Proc.Natl.Acad.Sci.Usa 2019.
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