Platinum in PDB 5z80: Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex

The binding sites of Platinum atom in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex (pdb code 5z80). This binding sites where shown within 5.0 Angstroms radius around Platinum atom.
In total 3 binding sites of Platinum where determined in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex, PDB code: 5z80:
Jump to Platinum binding site number: 1; 2; 3;

Platinum binding site 1 out of 3 in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 1 of Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt101 b:0.3 occ:1.00 PT2 A:9F0101 0.0 0.3 1.0 N49 A:9F0101 2.0 0.4 1.0 N35 A:9F0101 2.0 0.3 1.0 N41 A:9F0101 2.0 0.4 1.0 N42 A:9F0101 2.1 0.6 1.0 H49 A:9F0101 2.5 0.4 1.0 H41 A:9F0101 2.6 0.4 1.0 H9Y A:9F0101 2.6 0.6 1.0 H9X A:9F0101 2.6 0.5 1.0 H42 A:9F0101 2.6 0.7 1.0 C51 A:9F0101 2.8 0.4 1.0 C52 A:9F0101 2.8 0.6 1.0 C50 A:9F0101 2.9 0.4 1.0 C53 A:9F0101 2.9 0.7 1.0 C36 A:9F0101 3.0 0.3 1.0 C34 A:9F0101 3.0 0.3 1.0 H51 A:9F0101 3.0 0.5 1.0 H52 A:9F0101 3.0 0.7 1.0 H36 A:9F0101 3.0 0.3 1.0 H34 A:9F0101 3.0 0.4 1.0 H9L A:9F0101 3.4 0.4 1.0 H9O A:9F0101 3.4 0.7 1.0 H53 A:9F0101 3.8 0.8 1.0 H50 A:9F0101 3.8 0.5 1.0 H9N A:9F0101 3.8 0.6 1.0 H9M A:9F0101 3.8 0.5 1.0 C37 A:9F0101 4.3 0.3 1.0 C33 A:9F0101 4.3 0.3 1.0 C21 A:9F0101 4.8 0.2 1.0

Platinum binding site 2 out of 3 in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 2 of Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt101 b:0.4 occ:1.00 PT1 A:9F0101 0.0 0.4 1.0 N46 A:9F0101 2.0 0.5 1.0 N30 A:9F0101 2.0 0.4 1.0 N47 A:9F0101 2.0 0.5 1.0 N48 A:9F0101 2.1 0.5 1.0 H46 A:9F0101 2.5 0.5 1.0 H47 A:9F0101 2.6 0.6 1.0 H91 A:9F0101 2.6 0.6 1.0 H92 A:9F0101 2.6 0.5 1.0 H48 A:9F0101 2.6 0.5 1.0 C61 A:9F0101 2.8 0.6 1.0 C59 A:9F0101 2.8 0.5 1.0 C60 A:9F0101 2.9 0.6 1.0 C58 A:9F0101 2.9 0.6 1.0 C29 A:9F0101 3.0 0.4 1.0 C31 A:9F0101 3.0 0.3 1.0 H29 A:9F0101 3.0 0.5 1.0 H61 A:9F0101 3.0 0.6 1.0 H59 A:9F0101 3.0 0.6 1.0 H31 A:9F0101 3.1 0.4 1.0 H9V A:9F0101 3.4 0.6 1.0 H9T A:9F0101 3.4 0.6 1.0 H58 A:9F0101 3.8 0.6 1.0 H60 A:9F0101 3.8 0.7 1.0 H9U A:9F0101 3.8 0.6 1.0 H9W A:9F0101 3.8 0.6 1.0 O2 A:DT19 4.2 0.6 1.0 C28 A:9F0101 4.3 0.4 1.0 C32 A:9F0101 4.3 0.3 1.0 H3 A:DT19 4.4 0.7 1.0 C22 A:9F0101 4.8 0.3 1.0

Platinum binding site 3 out of 3 in the Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex


Mono view


Stereo pair view

A full contact list of Platinum with other atoms in the Pt binding site number 3 of Solution Structure For the 1:1 Complex of A Platinum(II)-Based Tripod Bound to A Hybrid-1 Human Telomeric G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Pt101 b:0.4 occ:1.00 PT3 A:9F0101 0.0 0.4 1.0 N45 A:9F0101 2.0 0.4 1.0 N44 A:9F0101 2.0 0.5 1.0 N43 A:9F0101 2.1 0.5 1.0 N25 A:9F0101 2.1 0.3 1.0 H45 A:9F0101 2.5 0.5 1.0 H90 A:9F0101 2.6 0.5 1.0 H44 A:9F0101 2.6 0.5 1.0 H43 A:9F0101 2.6 0.5 1.0 H9Z A:9F0101 2.6 0.5 1.0 C56 A:9F0101 2.8 0.5 1.0 C55 A:9F0101 2.8 0.5 1.0 C54 A:9F0101 2.8 0.5 1.0 C57 A:9F0101 2.9 0.6 1.0 C24 A:9F0101 3.0 0.3 1.0 C26 A:9F0101 3.0 0.3 1.0 H55 A:9F0101 3.0 0.5 1.0 H56 A:9F0101 3.0 0.5 1.0 H24 A:9F0101 3.0 0.4 1.0 H26 A:9F0101 3.0 0.4 1.0 H9P A:9F0101 3.2 0.6 1.0 H9S A:9F0101 3.4 0.6 1.0 H57 A:9F0101 3.8 0.7 1.0 H9R A:9F0101 3.8 0.5 1.0 H54 A:9F0101 3.8 0.6 1.0 H9Q A:9F0101 3.8 0.5 1.0 C23 A:9F0101 4.3 0.3 1.0 C27 A:9F0101 4.3 0.3 1.0 C20 A:9F0101 4.8 0.3 1.0 O4 A:DT8 4.9 0.8 1.0

W.Liu, Y.F.Zhong, L.Y.Liu, C.T.Shen, W.Zeng, F.Wang, D.Yang, Z.W.Mao. Solution Structures of Multiple G-Quadruplex Complexes Induced By A Platinum(II)-Based Tripod Reveal Dynamic Binding Nat Commun V. 9 3496 2018.
ISSN: ESSN 2041-1723
PubMed: 30158518
DOI: 10.1038/S41467-018-05810-4